End-tidal concentration of sevoflurane for optimal surgical conditions in pregnant sheep: a pragmatic approach to a retrospective observational study.

Autor: Bleeser T; Department of Anesthesiology, UZ Leuven, Department of Cardiovascular Sciences, Group Biomedical Sciences., Vergote S; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences., Basurto D; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences., Valenzuela I; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences., Joyeux L; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences.; Division of Pediatric Surgery, Department of Surgery, Texas Children's Hospital and Baylor College of Medicine., Russo F; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences., Kunpalin Y; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences., Emam D; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences.; Department of Obstetrics and Gynecology, University Hospitals Tanta., VAN DE Velde M; Department of Anesthesiology, UZ Leuven, Department of Cardiovascular Sciences, Group Biomedical Sciences., Devroe S; Department of Anesthesiology, UZ Leuven, Department of Cardiovascular Sciences, Group Biomedical Sciences., Deprest J; Department of Obstetrics and Gynecology, UZ Leuven, Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences.; Institute for Women's Health, University College London., Rex S; Department of Anesthesiology, UZ Leuven, Department of Cardiovascular Sciences, Group Biomedical Sciences.
Jazyk: angličtina
Zdroj: The Journal of veterinary medical science [J Vet Med Sci] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25.
DOI: 10.1292/jvms.24-0354
Abstrakt: The aim of this pragmatic approach to retrospective observational study was to identify the end-tidal concentration of sevoflurane which was associated with optimal surgical conditions (i.e., absence of any movement, coughing and straining) in 127 pregnant sheep. Optimal surgical conditions were observed in 90% of the ewes with an end-tidal concentration of sevoflurane of 2.4 Vol-% [95% CI: 2.2; 2.8] during minimal-mild nociceptive stimuli (placement of arterial catheter, bladder catheter, shaving), with 4.4 Vol-% [95% CI: 4.0; 5.2] during maternal laparotomy and hysterotomy and with 4.4 Vol-% [95% CI: 3.9; 5.8] during subsequent manipulation of the uterus and fetal surgery.
Databáze: MEDLINE