Hidden MODY in Young Lean Women with Mild Glucose Intolerance Detected During Health Check-ups: Potential for Improved Pregnancy Outcomes Through Preconception Care.

Autor: Osaki A; Division of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan., Ozawa A; Division of Fundamental Nursing, Department of Nursing, Gunma University, Japan., Morita A; Graduate School of Health Science Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Japan., Higeta D; Graduate School of Health Science Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Japan., Suda S; Graduate School of Health Science Department of Pediatrics, Gunma University Graduate School of Medicine, Japan., Ohtsu Y; Graduate School of Health Science Department of Pediatrics, Gunma University Graduate School of Medicine, Japan., Yoshino S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan., Matsumoto S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan., Horiguchi K; Division of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan., Yamada E; Division of Endocrinology and Metabolism, Department of Internal Medicine, Gunma University Graduate School of Medicine, Japan.
Jazyk: angličtina
Zdroj: Internal medicine (Tokyo, Japan) [Intern Med] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25.
DOI: 10.2169/internalmedicine.4244-24
Abstrakt: Mild glucose intolerance (positive urine glucose or mild hyperglycemia) during health checkups in young, lean women may require specialist consultation. We herein report a 31-year-old Japanese woman with mild hyperglycemia detected during a checkup who was diagnosed with overt diabetes in pregnancy and HNF4A-MODY postpartum, without prior follow-up. This case highlights the following: MODY may be present in young, lean women with mild glucose intolerance, and preconception care may improve pregnancy outcomes. Fetal outcomes vary with MODY subtype. Preconception care is important.
Databáze: MEDLINE
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