The emerging role of Never-in-Mitosis A - Related Kinases in the endothelium.

Autor: Barabutis N; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA. Electronic address: barabutis@ulm.edu., Fakir S; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
Jazyk: angličtina
Zdroj: The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2024 Dec; Vol. 177, pp. 106679. Date of Electronic Publication: 2024 Oct 24.
DOI: 10.1016/j.biocel.2024.106679
Abstrakt: The endothelium forms a monolayer, which functions to ensure tissue homeostasis. Barrier hyperpermeability has been associated with lung, brain and eye disease. An emerging body of evidence reports the involvement of Never-in-Mitosis A - Related Kinases in vascular responses, suggesting their value as potential therapeutic targets in endothelial-dependent disorders.
Competing Interests: Declaration of Competing Interest The authors declare no conflict of interests
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Databáze: MEDLINE