Epidemiological analysis of pediculosis and the distribution of kdr mutation frequency in head lice populations in Torbat Heydarieh city of Khorasan Razavi Province, Northeastern Iran.

Autor: Taheri M; Cellular & Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences (UMSU), P. O. Box: 5756115198, Urmia, Iran.; Department of Vector Biology and Control of Diseases, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran., Ghahvechi Khaligh F; Department of Vector Biology and Control of Diseases, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran.; Social Determinants of Health Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran., Hanafi-Bojd AA; Department of Vector Biology and Control of Diseases, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.; Zoonoses Research Center, Tehran University of Medical Sciences, Tehran, Iran., Khalkhali HR; Department of Biostatistics and Epidemiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran., Dashti K; Department of Vector Biology and Control of Diseases, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Badakhshan M; Department of Vector Biology and Control of Diseases, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran.; Social Determinants of Health Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran., Gholizadeh S; Cellular & Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences (UMSU), P. O. Box: 5756115198, Urmia, Iran. sabergholizadehh@gmail.com.; Department of Vector Biology and Control of Diseases, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran. sabergholizadehh@gmail.com.
Jazyk: angličtina
Zdroj: BMC research notes [BMC Res Notes] 2024 Oct 25; Vol. 17 (1), pp. 323. Date of Electronic Publication: 2024 Oct 25.
DOI: 10.1186/s13104-024-06940-3
Abstrakt: Head lice infestations are the most prominent ectoparasitic infection in the world, including Iran, particularly among school children. Recently, numerous cases of infestation have been reported in various provinces of the country. This study aimed to investigate the prevalence of head louse infestations and analyze kdr gene sequences in terms of resistance mutations in the Torbat-e Heydarieh, Mahvelat, and Zaveh cities of Khorasan Razavi Province, Northeast Iran. The data related to the epidemiological and demographic history of head lice populations were extracted from their medical records and analyzed in Excel software. After extracting the genomic DNA, the kdr fragment was amplified using specific primers. The sequences were also analyzed using bioinformatics software. The prevalence of head louse infestations was 1.59% and 1.7% during 2016 and 2017, respectively. Sequence analysis revealed the frequency distribution of two kdr haplotypes, I and V, in the study areas. The increase in head louse infestations in recent years and the simultaneous presence of kdr mutations indicate the need for new treatments and monitoring/controlling resistance to head louse insecticides.
(© 2024. The Author(s).)
Databáze: MEDLINE
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