The Use of a Specialized Oral Nutritional Supplement in the Management of Chronic Wounds in Patients With and Without Diabetes Mellitus: Cost-Effectiveness Analysis.

Autor: Mehl AA; Research Department at Adriano Mehl Consultancy Ltd, Brazil., Pagliosa VMR; Nestlé Healthscience, Brazil., Tauil DA; Nestlé Healthscience, Brazil., Schilling Rosenfeld VA; Nestlé Healthscience, Brazil. Electronic address: valeria.rosenfeld@br.nestle.com.
Jazyk: angličtina
Zdroj: Value in health regional issues [Value Health Reg Issues] 2024 Oct 24; Vol. 45, pp. 101049. Date of Electronic Publication: 2024 Oct 24.
DOI: 10.1016/j.vhri.2024.101049
Abstrakt: Objectives: To analyze the cost-effectiveness of the use of a specialized oral nutritional supplement (ONS) with proline, arginine, vitamins, and micronutrients to stimulate the healing of chronic wounds in patients with and without diabetes mellitus.
Methods: This is a quantitative study on cost-effectiveness. This model used a decision-tree model followed by a budget impact analysis from the Brazilian public healthcare system's perspective. For this analysis, the population and data from a randomized trial of an oral specialized-ONS-containing supplement were considered. For budget impact analysis, an epidemiologic approach was used to estimate the eligible population. The eligible population comprised 3 different groups: patients with pressure ulcers, patients with vascular ulcers, and patients with diabetic feet. The budget impact analysis used the results of the cost-effectiveness analysis.
Results: The results demonstrate that the use of specialized ONS, when compared with control ONS, proved to be cost saving (cheaper and more effective), considering the presence of predictive scar factor. The aggregated budget impact analysis results shows that the total reduction of costs after 5 years is USD 332 628 437.00.
Conclusions: The use of a specialized ONS was cost-effective in the healing of chronic wounds, when compared with control. The budget impact analysis showed a significant decrease in costs in a 5-year time horizon for the management of pressure ulcers, vascular ulcers, and diabetic feet.
Competing Interests: Author Disclosures Author disclosure forms can be accessed below in the Supplemental Material section.
(Copyright © 2024 International Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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