Comparison between invasive cardiac output and left ventricular assist device flow parameter.

Autor:	Segev A; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Copeland V; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Sokolski M; Clinic of Cardiac Transplantation and Mechanical Circulatory Support, Institute of Heart Diseases, University Hospital, Wroclaw Medical University, Wroclaw, Poland., Azaria S; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Morgan A; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Maor E; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Jura M; Clinic of Cardiac Transplantation and Mechanical Circulatory Support, Institute of Heart Diseases, University Hospital, Wroclaw Medical University, Wroclaw, Poland.; Department of Physiology, Wroclaw Medical University, Wroclaw, Poland., Wilk M; Clinic of Cardiac Transplantation and Mechanical Circulatory Support, Institute of Heart Diseases, University Hospital, Wroclaw Medical University, Wroclaw, Poland.; Student Scientific Club of Transplantology and Advanced Therapies of Heart Failure, Wroclaw Medical University, Wrocław, Poland., Przybylski R; Clinic of Cardiac Transplantation and Mechanical Circulatory Support, Institute of Heart Diseases, University Hospital, Wroclaw Medical University, Wroclaw, Poland., Freimark D; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Tal-Ben Ishay R; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Regev U; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Fardman A; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel., Grupper A; The Leviev Heart Center, Sheba Medical Center, Ramat-Gan, Israel.
Jazyk:	angličtina
Zdroj:	European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery [Eur J Cardiothorac Surg] 2024 Nov 04; Vol. 66 (5).
DOI:	10.1093/ejcts/ezae383
Abstrakt:	Objectives: To evaluate the correlation between left ventricular assist device flow parameter and invasive cardiac output measurements. Methods: We retrospectively evaluated right heart catheterization examinations performed in left ventricular assist device patients from 2 tertiary medical centres. We evaluated the correlation between cardiac output measurement methods (indirect Fick and thermodilution) and pump flow parameter using linear regression, and the agreement was graphically displayed using Bland-Altman plot technique. Clinical, echocardiographic, pump and haemodynamic parameters were compared between patients with and without discordance, defined as at least a 20% difference between measurements. Results: The study population consisted of 102 patients [median age 58 (51-64), 86% males, 17 ± 12 months post left ventricular assist device implantation] with a total of 544 measurements compared. Discordance between measurements was present in 102 of 226 (45%) comparisons between indirect Fick and pump flow and in 72 of 161 (48%) between thermodilution and pump flow. A comparison of indirect Fick and left ventricular assist device exhibited a statistical correlation of R = 0.751, and that of thermodilution and left ventricular assist device of R = 0.789. Parameters associated with the presence of discordance between cardiac output measurements included a higher rate of aortic valve opening, lower indirect Fick and higher thermodilution cardiac output. After excluding the lowest tertile of indirect Fick cardiac output values, the correlation between measurements improved (thermodilution: R = 0.879 and indirect Fick: R = 0.843, P < 0.001). Conclusions: The current left ventricular assist device flow parameter provides an estimation of cardiac output that correlates well with indirect Fick and exhibits the strongest correlation with thermodilution. This correlation was stronger after excluding lower cardiac output values. (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
Databáze:	MEDLINE
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