Autor: |
Lacaita PG; Department Radiology, Innsbruck Medical University, 6020 Innsbruck, Austria., Luger A; Department Radiology, Innsbruck Medical University, 6020 Innsbruck, Austria., Plank F; Department Internal Medicine, Tyrol Clinicum Hall, 6060 Hall, Austria., Barbieri F; Department of Cardiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Hindenburgdamm 30, 12203 Berlin, Germany., Beyer C; Department Radiology, Innsbruck Medical University, 6020 Innsbruck, Austria., Thurner T; Gesundheitszentrum Lanserhof, 6072 Lans, Austria., Scharll Y; Department Radiology, Innsbruck Medical University, 6020 Innsbruck, Austria., Deeg J; Department Radiology, Innsbruck Medical University, 6020 Innsbruck, Austria., Widmann G; Department Radiology, Innsbruck Medical University, 6020 Innsbruck, Austria., Feuchtner GM; Department Radiology, Innsbruck Medical University, 6020 Innsbruck, Austria. |
Abstrakt: |
(1) Background: The novel SARS-CoV-2 virus infects the endothelium. Vasculitis may lead to specific coronary artery wall lesions. Coronary computed tomography angiography (CTA) imaging findings have not been systematically reported. The aim of this study was to describe a case series using CTA. (2) Methods: Patients with recent RT-PCR confirmed SARS-CoV-2 infection referred for coronary CTA for clinical indications (e.g., chest pain, troponin+, and ECG abnormalities) were included. Coronary CTA findings, such as atypical coronary lesions suggestive of vasculitis, perivascular inflammation measured by using pericoronary fat attenuation (PCAT) index, coronary artery disease, and extracoronary findings were collected. (3) Results: Results for 12 patients (54.8 ± 22 years; four females) with SARS-CoV-2 infection within 60 days (four acute care and eight stable patients) are reported. Time to positive RT-PCR was a mean of 15.1 days (range, 0-51). In four acute patients with signs of myocardial injury, plaque rupture (n = 1), hyperenhancing myocardium/MINOCA (n = 1), MINOCA (n = 1), and pericarditis with acute heart failure (LVEF 20%) (n = 1) were found. All (100%) had pericardial effusion and signs of perivascular inflammation. Among eight stable patients, pericardial effusion or perivascular inflammation were found in only two (25%). Coronary artery disease was ruled out in five (62.5%) (4) Conclusions: Coronary CTA is a useful imaging modality in the diagnostic work up of patients with COVID-19 infection, and is able to describe coronary and other cardiac abnormalities. |