| Autor: |
Soria-Comes T; Medical Oncology Department, Hospital Universitario Doctor Peset, 46017 Valencia, Spain., Climent-Gregori M; Pneumology Department, Hospital Universitario Doctor Peset, 46017 Valencia, Spain., Maestu-Maiques I; Medical Oncology Department, Hospital Universitario Doctor Peset, 46017 Valencia, Spain., Inchaurraga-Álvarez I; Pneumology Department, Hospital Universitario Doctor Peset, 46017 Valencia, Spain., Cuenca-Martínez F; Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain., Cauli O; Department of Nursing, University of Valencia, 46010 Valencia, Spain.; Frailty Research Organized Group, University of Valencia, 46010 Valencia, Spain.; Chair of Healthy, Active and Participative Ageing, University of Valencia, 46010 Valencia, Spain., Martínez-Arnau FM; Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain.; Frailty Research Organized Group, University of Valencia, 46010 Valencia, Spain.; Chair of Healthy, Active and Participative Ageing, University of Valencia, 46010 Valencia, Spain. |
| Jazyk: |
angličtina |
| Zdroj: |
Clinics and practice [Clin Pract] 2024 Oct 18; Vol. 14 (5), pp. 2202-2216. Date of Electronic Publication: 2024 Oct 18. |
| DOI: |
10.3390/clinpract14050173 |
| Abstrakt: |
Background: Lung cancer carries a high burden of systemic symptoms, including in survivors, leading to a reduced quality of life (QoL). We assessed whether a 12-week multicomponent supervised exercise programme, including muscular strength and aerobic training, was beneficial in patients who had undergone surgery for early non-small cell lung cancer (NSCLC) in terms of physical performance, QoL, and metabolic and nutritional analytical parameters. Methods: Physical performance was measured by gait speed, handgrip strength, 30 s sit-to-stand (30s-STS) test repetitions, distance covered in the 6 min walk test (6MWT), and the Short Physical Performance Battery (SPPB) score. QoL was assessed with the EORTC-QLQ-C30 questionnaire. Blood glucose, cholesterol, triglycerides, total proteins, albumin, pre-albumin, creatinine, c-reactive protein, insulin-growth factor 1 (IGF-1), and the haemoglobin and hematocrit percentages were measured before and after the intervention in order to observe any beneficial effects related to metabolic markers. Results: After the intervention, the mean scores for the 6MWT ( p < 0.001), STS ( p < 0.001), 6MWT ( p < 0.01), and SPPB ( p < 0.01) had significantly improved. However, handgrip strength and nutritional analytical were unchanged. The EORTC-QLQ-C30 functions and symptoms significantly improved after the intervention ( p < 0.05 and p < 0.01, respectively). A significant decrease in cholesterol, triglycerides, and IGF-1 and a significant increase in pre-albumin in blood was also observed post-intervention ( p < 0.05). Conclusions: This supervised, community-based 12-week multicomponent was feasible (adherence rate 70.35%) and provided benefits not only to physical performance but also to the quality of life of patients with NSCLC. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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