360° CZT-SPECT/CT cameras: 99m Tc- and 177 Lu-phantom-based evaluation under clinical conditions.
| Autor: | Hoog C; Medical Physics Department, Institut Godinot Comprehensive Cancer Center, Reims, France. christopher.hoog@reims.unicancer.fr., Koulibaly PM; Department of Diagnostic Radiology and Nuclear Medicine, Antoine Lacassagne Comprehensive Cancer Center, Université Nice-Côte d'Azur, 33 Avenue de Valombrose, 06189, Nice, France., Sas N; Department of Medical Physics, Jean Perrin Comprehensive Cancer Center, 63000, Clermont-Ferrand, France., Imbert L; Department of Nuclear Medicine and Nancyclotep Imaging Platform, CHRU-Nancy, Université de Lorraine, 54000, Nancy, France., Le Rouzic G; Nuclear Medicine Department, CHU Orleans, 14 Avenue de l'Hôpital, 45100, Orleans, France., Popoff R; Department of Medical Physics, Georges-François Leclerc Cancer Center, 1 Rue du Professeur Marion, 21000, Dijon, France.; ICMUB, UMR 6302, CNRS, Dijon, France., Badel JN; Centre de Lutte Contre le Cancer Léon-Bérard, CREATIS CNRS UMR 5220 INSERM U 1044, Université de Lyon, INSA-Lyon, Lyon, France., Ferrer L; Medical Physics Department, ICO René Gauducheau, Saint Herblain, 44805, France.; CRCINA, UMR 1232, INSERM, Nantes, France. |
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| Jazyk: | angličtina |
| Zdroj: | EJNMMI physics [EJNMMI Phys] 2024 Oct 24; Vol. 11 (1), pp. 89. Date of Electronic Publication: 2024 Oct 24. |
| DOI: | 10.1186/s40658-024-00684-6 |
| Abstrakt: | Purpose: For the first time, three currently available 360° CZT-SPECT/CT cameras were compared under clinical conditions using phantom-based measurements. Methods: A 99m Tc- and a 177 Lu-customized NEMA IEC body phantom were imaged with three different cameras, StarGuide (GE Healthcare), VERITON-CT versions 200 (V200) and 400 (V400) (Spectrum Dynamics Medical) under the same clinical conditions. Energy resolution and volumetric sensitivity were evaluated from energy spectra. Vendors provided the best reconstruction parameters dedicated to visualization and/or quantification, based on their respective software developments. For both 99m Tc- and 177 Lu-phantoms, noise level, quantification accuracy, and recovery coefficient (RC) were performed with 3DSlicer. Image quality metrics from an approach called "task-based" were computed with iQMetrix-CT on 99m Tc visual reconstructions to assess, through spatial frequencies, noise texture in the background (NPS) and contrast restitution of a hot insert (TTF). Spatial resolution indices were calculated from frequencies corresponding to TTF Results: Despite the higher sensitivity of VERITON cameras and the enhanced energy resolution of the V400 (3.2% at 140 keV, 5.2% at 113 keV, and 3.6% at 208 keV), StarGuide presents comparable image quality. This highlights the need to differentiate sensitivity from count quality, which is influenced by hardware design (collimator, detector block) and conditions image quality as well as the reconstruction process (algorithms, scatter correction, noise regulation). For 99m Tc imaging, the quantitative image optimization approach based on RC Conclusions: The three cameras have equivalent potential for 99m Tc imaging, while StarGuide and V400 have demonstrated higher potential for 177 Lu. Dedicated visual or quantitative reconstructions offer better specific performances compared to the unified visual/quantitative reconstruction. The task-based approach appears to be promising for in-depth comparison of images in the context of system characterization/comparison and protocol optimization. (© 2024. The Author(s).) |
| Databáze: | MEDLINE |
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