Pulmonary arterial hypertension: updates and perspective with newer therapies.

Autor: Prasad JD; Department of Respiratory Medicine, Alfred Hospital, Melbourne, Victoria, Australia.; Department of Respiratory Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia., Williams TJ; Department of Respiratory Medicine, Alfred Hospital, Melbourne, Victoria, Australia., Whitford HM; Department of Respiratory Medicine, Alfred Hospital, Melbourne, Victoria, Australia.
Jazyk: angličtina
Zdroj: Internal medicine journal [Intern Med J] 2024 Dec; Vol. 54 (12), pp. 1944-1951. Date of Electronic Publication: 2024 Oct 23.
DOI: 10.1111/imj.16515
Abstrakt: Pulmonary arterial hypertension (PAH) is a rare condition for which a remarkable change has been witnessed in the epidemiology, assessment and treatment landscape over the last three decades. Well-established registries from the Western world have not only highlighted the shift in the epidemiology to an older, more comorbid cohort but have also identified markers of prognosis that have been validated as part of risk stratification scores in multiple cohorts. The emphasis on early identification through a systematic assessment pathway and the option of upfront combination therapy with serial risk stratification assessment has laid the foundation for the standard of care and improved prognosis. This review provides an update on the assessment and newer therapies for PAH.
(© 2024 Royal Australasian College of Physicians.)
Databáze: MEDLINE
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