The Importance of Multidisciplinary Teams in the Early Detection and Management of Disseminated Nannizziopsis Infections in Solid Organ Transplant Recipients: A Case-Based Review.
| Autor: | Soyele AC; Intensive Care Unit, University of Maryland Medical Center, Baltimore, USA., Kassa S; Intensive Care Unit, University of Maryland Medical Center, Baltimore, USA., Zaffar D; Internal Medicine, University of Maryland Medical Center, Baltimore, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Sep 22; Vol. 16 (9), pp. e69920. Date of Electronic Publication: 2024 Sep 22 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.69920 |
| Abstrakt: | This case report presents the clinical course of a 58-year-old female renal transplant patient with a complex medical history, including type 2 diabetes mellitus, hypertension, and chronic immunosuppression, who developed a disseminated Nannizziopsis obscura infection. The patient presented with persistent left leg pain and rapidly progressed to multisystem involvement, including central nervous system abscesses. Despite aggressive antifungal therapy and multidisciplinary management, her condition deteriorated, leading to a transition to palliative care. This report highlights the challenges in diagnosing and managing rare fungal infections in immunocompromised patients, highlighting the importance of early detection, advanced imaging, and a coordinated approach to care. The case also emphasizes the ethical considerations in balancing aggressive treatment with quality of life in terminal conditions. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Soyele et al.) |
| Databáze: | MEDLINE |
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