Border-ownership tuning determines the connectivity between V4 and V1 in the macaque visual system.

Autor: Jeurissen D; Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, Amsterdam, the Netherlands.; Department of Neuroscience, Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.; Center for Neural Science, New York University, 4 Washington Pl, New York, NY, USA., van Ham AF; Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, Amsterdam, the Netherlands., Gilhuis A; Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, Amsterdam, the Netherlands., Papale P; Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, Amsterdam, the Netherlands., Roelfsema PR; Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, Amsterdam, the Netherlands.; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, VU University, De Boelelaan 1085, Amsterdam, The Netherlands.; Neurosurgery department, Academic University Medical Center, Postbus 22660, Amsterdam, The Netherlands.; Laboratory of Visual Brain Therapy, Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris, France., Self MW; Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, Amsterdam, the Netherlands. m.self@nin.knaw.nl.; School of Psychology and Neuroscience, University of Glasgow, Glasgow, Scotland. m.self@nin.knaw.nl.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2024 Oct 23; Vol. 15 (1), pp. 9115. Date of Electronic Publication: 2024 Oct 23.
DOI: 10.1038/s41467-024-53256-8
Abstrakt: Cortical feedback connections are extremely numerous but the logic of connectivity between higher and lower areas remains poorly understood. Feedback from higher visual areas to primary visual cortex (V1) has been shown to enhance responses on perceptual figures compared to backgrounds, an effect known as figure-background modulation (FBM). A likely source of this feedback are border-ownership (BO) selective cells in mid-tier visual areas (e.g. V4) which represent the location of figures. We examined the connectivity between V4 cells and V1 cells using noise-correlations and micro-stimulation to estimate connectivity strength. We show that connectivity is consistent with a model in which BO-tuned V4 cells send positive feedback in the direction of their preferred figure and negative feedback in the opposite direction. This connectivity scheme can recreate patterns of FBM observed in previous studies. These results provide insights into the cortical connectivity underlying figure-background perception and establish a link between FBM and BO-tuning.
(© 2024. The Author(s).)
Databáze: MEDLINE
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