Indoor and outdoor artificial light-at-night (ALAN) and cancer risk: A systematic review and meta-analysis of multiple cancer sites and with a critical appraisal of exposure assessment.

Autor: Palomar-Cros A; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain; Universitat Pompeu Fabra, Barcelona, Spain; CIBERESP, Madrid, Spain; Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain., Deprato A; Division of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada., Papantoniou K; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain; Department of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria., Straif K; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain; Boston College, Chestnut Hill, MA, United States., Lacy P; Division of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada., Maidstone R; Division of Immunology, Immunity to Infection, and Respiratory Medicine, University of Manchester, Manchester, United Kingdom., Adan A; Department of Clinical Psychology and Psychobiology, University of Barcelona, Barcelona, Spain; Institute of Neurosciences, University of Barcelona, Barcelona, Spain., Haldar P; Department of Medical Laboratory Technology, Supreme Institute of Management and Technology, Mankundu, India., Moitra S; Department of Allergy and Immunology, Apollo Gleneagles Hospital, Kolkata, India., Navarro JF; Department of Psychobiology and Methodology of Behavioural Sciences, University of Málaga, Málaga, Spain., Durrington H; Division of Immunology, Immunity to Infection, and Respiratory Medicine, University of Manchester, Manchester, United Kingdom., Moitra S; Division of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; Canadian VIGOUR Centre, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; Bagchi School of Public Health, Ahmedabad University, Ahmedabad, Gujarat, India., Kogevinas M; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain; Universitat Pompeu Fabra, Barcelona, Spain; CIBERESP, Madrid, Spain; Hospital del Mar Research Institute, Barcelona, Spain., Harding BN; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain; Universitat Pompeu Fabra, Barcelona, Spain; CIBERESP, Madrid, Spain. Electronic address: barbara.harding@isglobal.org.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2024 Dec 10; Vol. 955, pp. 177059. Date of Electronic Publication: 2024 Oct 20.
DOI: 10.1016/j.scitotenv.2024.177059
Abstrakt: Exposure to artificial light-at-night (ALAN) has been linked to cancer risk. Few meta-analyses on this topic have reviewed only breast cancer. This study aimed to systematically review and meta-analyze existing studies on ALAN exposure and cancer incidence, thoroughly evaluating exposure assessment quality. We considered observational studies (cohort, case-control, cross-sectional) on ALAN exposure (indoor and outdoor) and cancer incidence, measured by relative risk, hazard ratio, and odds ratio. We searched six databases, two registries, and Google Scholar from inception until April 17, 2024. Quality of studies was assessed using the Joanna Briggs Institute (JBI) critical appraisal tools. Random-effects meta-analysis was used to estimate relative risks (RR) and 95 % confidence intervals (CI) for ALAN exposures. We identified 9835 studies and included 28 for qualitative synthesis with 2,508,807 individuals (15 cohort, 13 case-control). Out of the included studies, 20 studies on breast cancer (731,493 individuals) and 2 studies on prostate cancer (53,254 individuals) were used for quantitative synthesis. Higher levels of outdoor ALAN were associated with breast cancer risk (meta-estimate = 1.12, 95 % CI 1.03-1.23 (I 2  = 69 %)). We observed a non-significant positive association between indoor ALAN levels and breast cancer risk (meta-estimate = 1.07, 0.95-1.21, I 2  = 60 %), and no differences by menopausal status. The meta-analysis for prostate cancer suggested a non-statistically significant increased risk for higher levels of outdoor ALAN (meta-estimate = 1.43, 0.75-2.72, I 2  = 90 %). In the qualitative synthesis, we observed positive associations with non-Hodgkin lymphoma and colorectal, pancreatic and thyroid cancer. We found an association between outdoor ALAN and breast cancer risk. However, most studies relied on satellite-images with a very low resolution (1 to 5 km, from the Defense Meteorological Program [DMSP]) and without information on color of light. Future studies with better exposure assessment should focus on investigating other cancer sites.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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