Plasmodium ovale Malaria in Travelers and Immigrants to the United States: A Case Series.
| Autor: | Mayhew JA; Ryan White Center for Global Health and Pediatric Infectious Diseases, Indiana University, Indianapolis, Indiana.; Department of Pediatric & Adolescent Medicine, Western Michigan University School of Medicine, Kalamazoo, Michigan., Alali M; Ryan White Center for Global Health and Pediatric Infectious Diseases, Indiana University, Indianapolis, Indiana., Enane LA; Ryan White Center for Global Health and Pediatric Infectious Diseases, Indiana University, Indianapolis, Indiana., Kirkpatrick LM; Ryan White Center for Global Health and Pediatric Infectious Diseases, Indiana University, Indianapolis, Indiana., John CC; Ryan White Center for Global Health and Pediatric Infectious Diseases, Indiana University, Indianapolis, Indiana. |
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| Jazyk: | angličtina |
| Zdroj: | The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22. |
| DOI: | 10.4269/ajtmh.24-0333 |
| Abstrakt: | Malaria in child travelers caused by Plasmodium ovale spp. is less well characterized than malaria due to other Plasmodium species. Commonly used diagnostic tests often lack adequate sensitivity to identify P. ovale spp., and a missed diagnosis may have serious consequences. We present a case series of eight children in the United States with P. ovale malaria, all of whom had traveled to or immigrated from malaria-endemic areas. Two children developed clinical malaria, including one with severe malaria; two had isolated splenomegaly; and four were asymptomatic siblings of the children with splenomegaly. Seven of the eight children had negative blood smear readings, and the diagnosis was made by polymerase chain reaction testing. Two children had concurrent P. malariae infection despite presumptive antimalarial treatment before immigration. These findings suggest a need for reconsideration of screening and diagnostic evaluation for P. ovale malaria in high-risk groups. |
| Databáze: | MEDLINE |
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