Measuring the impact: Severity of harm from laboratory errors in 195 tests.

Autor:	Çubukçu HC; Rare Diseases Department, General Directorate of Health Services, Turkish Ministry of Health, Ankara, Turkiye., Cihan M; Ordu University Education and Research Hospital, Ordu, Turkiye., Alp HH; Department of Biochemistry, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Turkiye., Bolat S; Medical Biochemistry Department, Sivas Cumhuriyet University, Sivas, Turkiye., Zengi O; Department of Medical Biochemistry, Health Science University, Istanbul Başakşehir Çam and Sakura City Hospital, Istanbul, Turkiye., Uçar KT; Department of Medical Biochemistry, Health Science University, Istanbul Başakşehir Çam and Sakura City Hospital, Istanbul, Turkiye., Topcu Dİ; Department of Medical Biochemistry, İzmir City Hospital, İzmir, Turkiye., Kılınçkaya MF; Department of Medical Biochemistry, Helse Møre og Romsdal, Molde, Norway., Özdemir H; Department of Medical Biochemistry, Faculty of Medicine, Manisa Celal Bayar University, Manisa, Turkiye.; Türkiye Health Data Research and Artificial Intelligence Applications Institute, Health Institutes of Türkiye, Istanbul, Turkiye., Gülşen M; Rare Diseases Department, General Directorate of Health Services, Turkish Ministry of Health, Ankara, Turkiye., Canbaz H; Department of Emergency Medicine, University of Yıldırım Beyazıt, Yenimahalle Training and Research Hospital, Ankara, Turkiye., Yücel D; Department of Medical Biochemistry, Lokman Hekim University, Ankara, Turkiye., Serdar MA; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, Ankara, Turkiye.
Jazyk:	angličtina
Zdroj:	American journal of clinical pathology [Am J Clin Pathol] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.
DOI:	10.1093/ajcp/aqae144
Abstrakt:	Objectives: This study aimed to objectively assess the potential severity of harm associated with erroneous results in 195 laboratory tests by surveying 514 specialist physicians and medical biochemistry experts. Methods: The survey obtained participants' (75 medical biochemists, 439 clinicians) opinions on severity of harm for the erroneous results of 195 tests. The comprehensive list of errors and their effects on test results were obtained from the literature, and then matched with severity of harm scores, from 1 (negligible effect) to 5 (life-threatening injury/death), obtained from the survey responses. Results: Participants perceived tests such as cardiac biomarkers, blood gases, coagulation parameters (activated partial thromboplastin time, prothrombin time, international normalized ratio, and dimerized plasmin fragment D), critical ions (potassium, sodium), toxic trace elements (lead, mercury), and specific serum drug levels (lithium, digoxin) to have a greater potential for patient harm in case of errors. Medical biochemistry specialists assigned higher severity scores to some laboratory tests, including total bilirubin, pseudocholinesterase, platelet indices, and some drug levels (cyclosporine, methotrexate, vancomycin). Conclusions: A substantial agreement (91%) was observed between medical biochemists and clinicians in terms of the most frequently chosen severity of harm score. The study provided objective severity scores and identified high-risk tests for targeted quality improvement. (© The Author(s) 2024. Published by Oxford University Press on behalf of American Society for Clinical Pathology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Databáze:	MEDLINE
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