Ankylosing spondylitis and atrial fibrillation: a contemporary overview.

Autor:	Konstantinou CS; First Department of Cardiology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Greece., Karakosta M; Department of Rheumatology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Greece., Venetsanopoulou AI; Department of Rheumatology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Greece., Korantzopoulos P; First Department of Cardiology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Greece., Voulgari PV; Department of Rheumatology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Greece. pvoulgar@uoi.gr.
Jazyk:	angličtina
Zdroj:	Clinical and experimental rheumatology [Clin Exp Rheumatol] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.
DOI:	10.55563/clinexprheumatol/ue8sp5
Abstrakt:	Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and it is associated with increased morbidity and mortality. AF is linked with inflammatory signalling while inflammation and oxidative stress promote atrial remodelling, favouring the development and perpetuation of the arrhythmia. On the other hand, ankylosing spondylitis (AS) is considered a chronic inflammatory rheumatic condition with flares and remissions that affects the axial skeleton and mainly young people. AS has been associated with an increased risk of valvular and aorta disease but its relationship with AF has not been studied well. Recent epidemiological evidence indicates an association between AS and AF. This brief review provides a concise overview of all available data regarding the association between AS and AF including the predictive role of electrocardiographic and echocardiographic markers. Several unresolved issues including the thromboembolic risk in this setting and the potential role of anti-inflammatory interventions are also discussed.
Databáze:	MEDLINE
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