Photocatalytic synthesis of β-amino acid derivatives from alkenes with alkyl formates.

Autor:	Ying CJ; College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. libindong@njust.edu.cn., Shao Y; College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. libindong@njust.edu.cn., Wan YC; College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. libindong@njust.edu.cn., Zheng M; School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, P. R. China., Hua LL; College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. libindong@njust.edu.cn., Zhan LW; College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. libindong@njust.edu.cn., Li BD; College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. libindong@njust.edu.cn., Hou J; College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. libindong@njust.edu.cn.
Jazyk:	angličtina
Zdroj:	Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.
DOI:	10.1039/d4cc04131c
Abstrakt:	The aminocarbonylation of alkenes is an efficient approach to synthesize important β-amino acid motifs. However, simple and convenient methods are still rare. Herein, we present a novel visible-light-mediated controllable three-component radical relay coupling of alkenes, alkyl formates and oxime esters. By the combination of hydrogen atom transfer and energy transfer processes, a series of β-amino esters could be obtained smoothly in one step under mild conditions. We expect that the approach can complement current methodologies for the synthesis of β-amino esters.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu