Clinicoepidemiological Profile of Retinopathy of Prematurity.

Autor: Sahu S; Department of Ophthalmology, Veer Surendra Sai Institute of Medical Sciences and Research, Burla, Sambalpur, IND., Behera S; Department of Ophthalmology, Veer Surendra Sai Institute of Medical Sciences and Research, Burla, Sambalpur, IND., Bishi G; Department of Ophthalmology, Veer Surendra Sai Institute of Medical Sciences and Research, Burla, Sambalpur, IND., Choudhury L; Department of Ophthalmology, Veer Surendra Sai Institute of Medical Sciences and Research, Burla, Sambalpur, IND., Mishra S; Department of Ophthalmology, Veer Surendra Sai Institute of Medical Sciences and Research, Burla, Sambalpur, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Sep 21; Vol. 16 (9), pp. e69831. Date of Electronic Publication: 2024 Sep 21 (Print Publication: 2024).
DOI: 10.7759/cureus.69831
Abstrakt: Purpose In previously performed studies, retinopathy of prematurity (ROP) has been shown to occur postpartum. As a result, mechanical ventilation and oxygen dependence were eventually connected to the development of ROP in these preterm children, and ROP prevalence is on the rise globally. Despite various improvements in childcare, ROP still tends to arise due to various risk factors associated with the disease. So, clinically the research was performed to determine the clinical and epidemiological profile of ROP. Materials and methods A total of 268 participants were to be enrolled in the study. It was an observational, cross-sectional study carried out at Department of Ophthalmology and Neonatal Intensive Care Unit in Veer Surendra Sai Institute of Medical Sciences and Research Centre, Burla, Sambalpur, Odisha, India. Ethical approval was provided on 30 November 2019. Results Overall 123 (46%) infants out of 268 infants developed retinopathy of prematurity. Majorly, the infants had stage 1 and stage 2 ROP. Most of the infants were male. Birth weight in ROP patients was 1000 g or less in 54% of infants, 1000-1500 g in 46% of infants and >1500 g in 33% of infants. Gestational age was found to be a predictor of retinopathy of prematurity. The adverse events that were found to be associated with retinopathy of prematurity were sepsis (53%), respiratory distress syndrome (RDS) (54.6%), intraventricular haemorrhage (IVH) (60%), anaemia (61.5%). Conclusion It has been observed that babies with higher birth weights and older gestations are also susceptible to developing ROP. Therefore, the greater birth weight newborns up to 1750 g and older gestational age babies >34 weeks should also be included in the screening criteria, especially if they have risk factors such as oxygen supplementation, sepsis, RDS, and anaemia.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Vimsar Institutional Research & Ethics Committee issued approval 19215/Dt.30.11.19/IST-228/19. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Sahu et al.)
Databáze: MEDLINE