Tongue microbiota in relation to the breathing preference in children undergoing orthodontic treatment.

Autor: Marincak Vrankova Z; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic.; Clinic of Maxillofacial Surgery, University Hospital Brno, Jihlavska 20, Brno, Czech Republic.; Clinic of Stomatology, Institution Shared With St. Anne´s University Hospital, Faculty of Medicine, Masaryk University, Pekarska 53, Brno, Czech Republic., Brenerova P; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic., Bodokyova L; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic., Bohm J; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic., Ruzicka F; Clinic of Microbiology, Institution Shared With St. Anne ́s University Hospital, Faculty of Medicine, Masaryk University, Pekarska 53, Brno, Czech Republic., Borilova Linhartova P; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic. petra.linhartova@recetox.muni.cz.; Clinic of Maxillofacial Surgery, University Hospital Brno, Jihlavska 20, Brno, Czech Republic. petra.linhartova@recetox.muni.cz.
Jazyk: angličtina
Zdroj: BMC oral health [BMC Oral Health] 2024 Oct 21; Vol. 24 (1), pp. 1259. Date of Electronic Publication: 2024 Oct 21.
DOI: 10.1186/s12903-024-05062-3
Abstrakt: Background: Mouth breathing (MB), a risk factor of oral dysbiosis and halitosis, is linked with craniofacial anomalies and pediatric obstructive sleep apnea. Here, we aimed to analyze tongue microbiota in children from the perspective of their breathing pattern before/during orthodontic treatment.
Methods: This prospective case-control study included 30 children with orthodontic anomalies, 15 with MB and 15 with nasal breathing (NB), matched by age, sex, and body mass index. All underwent orthodontic examination and sleep apnea monitoring. Tongue swabs were collected before starting (timepoint M0) and approx. six months into the orthodontic therapy (timepoint M6). Oral candidas and bacteriome were analyzed using mass spectrometry technique and 16S rRNA sequencing, respectively.
Results: MB was associated with higher apnea-hypopnea index. At M0, oral candidas were equally present in both groups. At M6, Candida sp. were found in six children with MB but in none with NB. No significant differences in bacterial diversity were observed between groups and timepoints. However, presence/relative abundance of genus Solobacterium was higher in children with MB than NB at M0.
Conclusions: Significant links between MB and the presence of genus Solobacterium (M0) as well as Candida sp. (M6) were found in children with orthodontic anomalies, highlighting the risk of halitosis in them.
(© 2024. The Author(s).)
Databáze: MEDLINE
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