Negative outcome in cutaneous Mycobacterium marinum infection treated with surgical intervention: Two-case report.
| Autor: | Sang B; Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China., Xia X, Liu Z |
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| Jazyk: | angličtina |
| Zdroj: | Medicine [Medicine (Baltimore)] 2024 Oct 18; Vol. 103 (42), pp. e40179. |
| DOI: | 10.1097/MD.0000000000040179 |
| Abstrakt: | Rationale: Mycobacterium marinum (M marinum), a slow-growing nontuberculous mycobacterium (NTM), is widely distributed in aquatic environments. It is a well-known cutaneous pathogen, which causes sporotrichosis-like lesions. Patient Concerns: In this report, we describe 2 cases of subcutaneous M marinum infection. Both patients underwent several surgical procedures at local hospitals, and despite optimal surgical site healing, new lesions appeared in adjacent sites. Diagnoses: Based on NTM culture, identification by gene sequencing, and matrix-assisted laser desorption ionization time-of-flight mass spectrometry, the diagnosis of subcutaneous NTM infection was confirmed. Interventions: The patients were treated with oral rifampicin 0.45 g/day and clarithromycin 1 g/day and oral doxycycline hydrochloride capsules (200 mg/day), respectively. Outcomes: Both patients were treated for 8 and 5 weeks, respectively, and the lesions healed. Lessons: Surgical debridement cannot compete with or impede NTM lymphatic spread; antimicrobial therapy is the first choice for the treatment of M marinum infections. Competing Interests: The authors have no conflicts of interest to disclose. (Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.) |
| Databáze: | MEDLINE |
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