Effectiveness of multidisciplinary interventions to improve blood culture efficiency and optimize antimicrobial utilization.

Autor:	Li Z; Department of Infection Prevention and Control, Guangdong Second Provincial General Hospital, Guangzhou, China., Hu K; Department of Science and Education, Guangdong Second Provincial General Hospital, Guangzhou, China., Wang T; Department of Infection Prevention and Control, Guangdong Second Provincial General Hospital, Guangzhou, China., Liu B; Department of Infection Prevention and Control, Guangdong Second Provincial General Hospital, Guangzhou, China., Zheng W; Department of Nursing, Guangdong Second Provincial General Hospital, Guangzhou, China., Zhou J; Department of Thyroid and Breast Surgery, Guangdong Second Provincial General Hospital, Guangzhou, China., Fan T; Department of Infection Prevention and Control, Guangdong Second Provincial General Hospital, Guangzhou, China., Lin M; Department of Laboratory Medicine, Guangdong Second Provincial General Hospital, Guangzhou, China., Lin G; Department of Infection Prevention and Control, Guangdong Second Provincial General Hospital, Guangzhou, China., Li S; Department of Pharmacy, Guangdong Second Provincial General Hospital, Guangzhou, China., Fan C; Department of Infection Prevention and Control, Guangdong Second Provincial General Hospital, Guangzhou, China.
Jazyk:	angličtina
Zdroj:	Frontiers in public health [Front Public Health] 2024 Oct 04; Vol. 12, pp. 1432433. Date of Electronic Publication: 2024 Oct 04 (Print Publication: 2024).
DOI:	10.3389/fpubh.2024.1432433
Abstrakt:	Background: The low positive rate of blood cultures often leads to downstream consequences. We present a summary of multidisciplinary interventions implemented by a tertiary referral hospital to improve blood culture efficiency and optimize antimicrobial usage. Methods: We evaluated the knowledge, attitude, and practice (KAP) of healthcare workers in a tertiary care hospital before and after intervention using a questionnaire. A multidisciplinary team was formed to implement the intervention, defining roles, standardizing procedures, continually improving education and feedback, and establishing incentive mechanisms. Regular quality control assessments are conducted on the responsible departments. Results: Following the intervention, the median submission time for blood culture specimens was reduced from 2.2 h to 1.3 h ( p  < 0.001). Additionally, the intervention group showed significant ( p < 0.05) increases in rates of positivity (9.9% vs. 8.6%), correct timing (98.7% vs. 89.6%), correct processing (98.1% vs. 92.3%), reduced contamination rates (0.9% vs. 1.4%), and disqualification rates (1.3% vs. 1.7%). The delivery rate of therapeutic antibacterial increased (16.1% vs. 15.2%), and the consumption of restrictive grade antimicrobial also significantly increased (26.7% vs. 22.9%). The intervention measures led to a substantial improvement in awareness and compliance with KAP of blood culture collection in the hospital. Hospital-wide antimicrobial usage deceased by 10.7% after intervention. Conclusion: A multidisciplinary collaborative model proves effective in improving blood culture efficiency and optimizing antimicrobial usage. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Li, Hu, Wang, Liu, Zheng, Zhou, Fan, Lin, Lin, Li and Fan.)
Databáze:	MEDLINE
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