Association of inpatient and outpatient pediatric palliative care with healthcare utilization and end-of-life outcomes in pediatric oncology.

Autor: Shamah RL; Emory University School of Medicine, Atlanta, Georgia, USA., George E; Maine Medical Center, Portland, Maine, USA., DeGroote NP; Aflac Cancer and Blood Disorders Center, Children's Hospital of Atlanta, Atlanta, Georgia, USA., Wasilewski K; Emory University School of Medicine, Atlanta, Georgia, USA.; Aflac Cancer and Blood Disorders Center, Children's Hospital of Atlanta, Atlanta, Georgia, USA., Brock KE; Emory University School of Medicine, Atlanta, Georgia, USA.; Aflac Cancer and Blood Disorders Center, Children's Hospital of Atlanta, Atlanta, Georgia, USA.
Jazyk: angličtina
Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2025 Jan; Vol. 72 (1), pp. e31387. Date of Electronic Publication: 2024 Oct 20.
DOI: 10.1002/pbc.31387
Abstrakt: Background: Pediatric palliative care (PPC) is associated with improved end-of-life (EOL) outcomes. Inpatient and outpatient PPC have unique roles during the disease course. Yet, it is unknown whether the location of PPC receipt (inpatient vs. outpatient) is associated with healthcare utilization and EOL outcomes for pediatric and adolescent and young adult oncology patients.
Procedure: A retrospective single-institution chart review of pediatric patients (age 0-28) with cancer who died between January 2015 and December 2022 was performed to compare EOL outcomes and healthcare utilization metrics among inpatient PPC, any outpatient PPC, and non-PPC recipients. Demographics and clinical factors were analyzed by PPC receipt location.
Results: Among 450 patients, 292 (64.9%) received PPC (inpatient only 35%, any outpatient 65%). Patients who died without receiving PPC dropped from 69% to 22% following development of an outpatient PPC clinic (p < .001). In the last 6 months, 1 month, and last week of life, inpatient PPC recipients spent more days admitted to the hospital and intensive care unit (all p < .001), and had more intensive medical interventions performed (p < .01). Outpatient PPC recipients were less likely to receive intravenous (IV) chemotherapy (p < .01) or intubation (p = .05), and more likely to receive hospice, die at home, and have an outpatient do-not-resuscitate order (all p < .001).
Conclusions: PPC receipt substantially increased after the creation of an outpatient PPC clinic, suggesting that outpatient PPC is critical in the provision of PPC to children with cancer. Outpatient PPC was associated with fewer hospital days, IV chemotherapy, and intubation at EOL, while increasing hospice enrollment and home death.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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