Hypericum perforatum L. (St. John's Wort) in broilers diet improve growth performance, intestinal microflora and immunity.

Autor:	İlhan Z; Faculty of Veterinary Medicine, Department of Microbiology, Cagıs Campus, Balıkesir University, Altıeylül, Balıkesir 10100, Türkiye. Electronic address: zilhan@balikesir.edu.tr., Zengin M; Faculty of Veterinary Medicine, Department of Animal Nutrition and Nutritional Diseases, Cagıs Campus, Balıkesir University, Altıeylül, Balıkesir 10100, Türkiye; Faculty of Veterinary Medicine, Department of Obstetrics and Gynecology, Görükle Campus, Bursa Uludağ University, Nilüfer, Bursa 16059, Türkiye., Bacaksız OK; Faculty of Veterinary Medicine, Department of Animal Nutrition and Nutritional Diseases, Cagıs Campus, Balıkesir University, Altıeylül, Balıkesir 10100, Türkiye., Demir E; Faculty of Veterinary Medicine, Department of Animal Nutrition and Nutritional Diseases, Cagıs Campus, Balıkesir University, Altıeylül, Balıkesir 10100, Türkiye., Ekin İH; Faculty of Veterinary Medicine, Department of Microbiology, Zeve Campus, Van Yüzüncu Yıl University, Van 65040, Türkiye., Azman MA; Faculty of Veterinary Medicine, Department of Animal Nutrition and Nutritional Diseases, Cagıs Campus, Balıkesir University, Altıeylül, Balıkesir 10100, Türkiye.
Jazyk:	angličtina
Zdroj:	Poultry science [Poult Sci] 2024 Dec; Vol. 103 (12), pp. 104419. Date of Electronic Publication: 2024 Oct 14.
DOI:	10.1016/j.psj.2024.104419
Abstrakt:	Hypericum perforatum L. (St. John's Wort) extract (HPE), powdered H. perforatum (PHP), and selenium (Se) on growth, intestinal flora, and immunity of broiler chicks were investigated. In total, 504 one-day-old broiler chicks were randomly allocated into 6 dietary treatments, which were then denoted as negative control (NC) group (basal diet), containing organic Se 0.2% in the starter and grower period as positive control (PC), containing 1% PHP in the starter and grower period, and HPE I, HPE II, and HPE III groups containing respectively, 1.5, 3.0, and 4.5 mL / kg HPE in the starter and grower period. The results on performance showed that a significant (P < 0.05) higher body weight of chickens in the HPE III group was observed when compared with that of the NC and PHP groups. Although average daily weight gain and feed intake are significant in the HPE III group, the difference in terms of total feed conversion rate was insignificant (P > 0.05). The liver weights in PC and HPE III were lower compared to HPE I (P < 0.05). The difference in total lactic acid bacteria count (TLABC) between the NC group and all HPE groups was found to be significant (P ˂ 0.05), in addition to TLABC was higher in the HPE III group than other groups (P = 0.001). The highest serum antibody titers to the Newcastle disease vaccine were determined in the HPE III group on the 24th, 35th, and 42nd days of age. IL-1B and IL-6 were found to be insignificant between the groups in chickens (P ˃ 0.05). TNF-α in the HPE III group was greatly increased than the other groups and significant compared to the NC and HPE I groups (P = 0.018). In conclusion, 4.5 mL / kg HPE, which has a low production cost and is easy to extract and without causing environmental problems, varied significantly in their impact on growth performance, intestinal microflora, and immunity of growing broilers. Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Ziya Ilhan reports financial support was provided by Balikesir University. Ziya Ilhan reports a relationship with Balikesir University that includes:. Ziya Ilhan has patent pending to No. The authors declare no conflicts of interest. They declare that they have no personal and/or financial relationships with any other corporation or individual that can inappropriately influence our work. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024. Published by Elsevier Inc.)
Databáze:	MEDLINE
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