Pelvic floor muscle electrical coupling in chronic pelvic pain: Insights into pathophysiology and botulinum toxin treatment effects.

Autor: Albaladejo-Belmonte M; Centro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, Edif. 8B, Camino de Vera SN, Valencia 46022, Spain. Electronic address: moalbel@ci2b.upv.es., Tarazona-Motes M; Servicio de Obstetricia y Ginecología, Hospital Universitario y Politécnico La Fe de Valencia, Valencia, Spain. Electronic address: tarazona_marmot@gva.es., Jose Nohales-Alfonso F; Servicio de Obstetricia y Ginecología, Hospital Universitario y Politécnico La Fe de Valencia, Valencia, Spain., De-Arriba M; Servicio de Obstetricia y Ginecología, Hospital Universitario y Politécnico La Fe de Valencia, Valencia, Spain. Electronic address: dearriba_margar@gva.es., Alberola-Rubio J; Sonda Devices S.L., Calle Colon, 1 - 4, Valencia 46004, Spain., Garcia-Casado J; Centro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, Edif. 8B, Camino de Vera SN, Valencia 46022, Spain. Electronic address: jgarciac@ci2b.upv.es.
Jazyk: angličtina
Zdroj: Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology [J Electromyogr Kinesiol] 2024 Dec; Vol. 79, pp. 102940. Date of Electronic Publication: 2024 Oct 11.
DOI: 10.1016/j.jelekin.2024.102940
Abstrakt: This study aimed to assess the electrical coupling between both pelvic floor muscle (PFM) sides (two-sided coupling) and within individual PFM sides (one-sided coupling) in chronic pelvic pain (CPP) before and after botulinum neurotoxin type A (BoNT/A) treatment. Surface electromyographic (sEMG) signals were recorded from the left and right PFM of 24 patients (P) with CPP before and after being treated with BoNT/A (Weeks 0,8,12,24). Recordings were also made in 24 healthy women (H). PFM two-sided and one-sided coupling was evaluated during contractions by the cross-correlation (CC) and the imaginary part of coherency (iCOH) of their sEMG signals. Significant differences between their values were assessed comparing P(0) vs. P(8,12,24) and H vs. P(0,8,12,24). This study showed that PFM two-sided coupling is similar across groups before treatment, while PFM one-sided coupling on the patients' most painful side is deranged before and also after BoNT/A treatment: amplitude coupling is lower (iCOH) than healthy women's. This could be justified by altered neuromotor control strategies developed as an adaptation to muscle pain, structural and electrical changes in PFM, and alterations in their innervation pattern, which may influence the onset, perpetuation, or recurrence of CPP after treatment.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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