Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants: Biofluorescence imaging system guided MRONJ surgery.

Autor: Park SH; Department of Oral and Maxillofacial Surgery, Jeonbuk Nation University Dental Hospital, 20, Geonji-ro, Deokjin-gu, Jeonju-si, Jeonbuk-do, 54907, Republic of Korea., Kim Y; Department of Dental Hygiene, Jeonju Kijeon College, Jeonju 54989, Republic of Korea., Yoon HC; BESTDEN Dental Clinic, 110 Teheran-ro 4F(Cambridge B/D), Gangnam-gu, Seoul, 06232, Republic of Korea., Yun PY; Department of Oral and Maxillofacial Surgery, Seoul National University Bundang Hospital, Bundang-gu, Seongnam-si, Republic of Korea; Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea., Ku JK; Department of Oral and Maxillofacial Surgery, Jeonbuk Nation University Dental Hospital, 20, Geonji-ro, Deokjin-gu, Jeonju-si, Jeonbuk-do, 54907, Republic of Korea; Department of Oral and Maxillofacial Surgery, Seoul National University Bundang Hospital, Bundang-gu, Seongnam-si, Republic of Korea. Electronic address: kujk@snubh.org.
Jazyk: angličtina
Zdroj: Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2024 Dec; Vol. 50, pp. 104370. Date of Electronic Publication: 2024 Oct 16.
DOI: 10.1016/j.pdpdt.2024.104370
Abstrakt: The decision of surgical margin for Medication-Related Osteonecrosis of the Jaw (MRONJ) surgery is challenging. Recently, a method involving biofluorescence imaging system (BIS) has been reported for its application in MRONJ surgery to live detection of pathologic bone tissue from vital bone, which cannot be distinguished during conventional surgery. This case series aimed to assess the outcomes of adjacent teeth and implants near the lesion site in MRONJ patients who underwent BIS-guided MRONJ surgery. This retrospective study was assessed the radiographic and clinical outcomes of seven patients who underwent MRONJ surgery with BIS guidance but chose not to remove adjacent teeth or implants near the lesion. A total of seven patients (1 male, 6 females, 77.2 ± 4.7 years) were included in the study. Four implants and four teeth adjacent to the lesion were preserved. Over an average duration of 8.7 months, all subjects exhibited normal soft tissue healing and function without any complications. In conclusion, the BIS guided MRONJ surgery can be considered a minimally invasive and effective approach.
Competing Interests: Declaration of competing interest One of the authors, Hong Cheol Yoon, is the current CEO of Qray-Pen device manufacturing company which were used for this research (AIOBIO, Seoul, Republic of Korea). All the other authors declare no conflict of interest.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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