Efficacy of High Flow Nasal Cannula in the Treatment of Patients with COVID-19 with Acute Respiratory Distress Syndrome: Results of Single Centre Study in Vietnam.
| Autor: | Duong-Quy S; Biomedical Research Centre, Lam Dong Medical College, Dalat City, Vietnam. sduongquy.jfvp@gmail.com.; Outpatient Department of Pham Ngoc, Thach University, Ho Chi Minh City, Vietnam. sduongquy.jfvp@gmail.com.; Immuno-Allergology and Respiratory Department, Hershey Medical Center, Hershey, PA, USA. sduongquy.jfvp@gmail.com., Huynh-Truong-Anh D; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Tang-Thi-Thao T; Biomedical Research Centre, Lam Dong Medical College, Dalat City, Vietnam., Nguyen-Ngoc-Phuong T; Outpatient Department of Pham Ngoc, Thach University, Ho Chi Minh City, Vietnam., Hoang-Phi-Tuyet P; Biomedical Research Centre, Lam Dong Medical College, Dalat City, Vietnam., Nguyen-Tuan A; Biomedical Research Centre, Lam Dong Medical College, Dalat City, Vietnam., Nguyen-Van T; Biomedical Research Centre, Lam Dong Medical College, Dalat City, Vietnam., Nguyen-Chi T; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Nguyen-Thi-Kim T; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Nguyen-Quang T; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Tran-Ngoc-Anh T; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Nguyen-Van-Hoai N; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Do-Thi-Thu M; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Hoang-Thi-Xuan H; Nursing Faculty, Phenikaa University, Hanoi, Vietnam., Nguyen-Duy T; National Institute for Control of Vaccines and Biologicals, Ministry of Health, Hanoi City, Vietnam., Nguyen-Hai C; Department of Tuberculosis and Respiratory Pathology, Military Hospital 175, Ho Chi Minh City, Vietnam., Huynh-Anh T; Department of Respiratory Diseases, Hoan My General Hospital, Cái Răng, Can Tho Province, Vietnam., Vu-Tran-Thien Q; Department of Respiratory Functional Exploration, University Medical Centre, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Bui-Diem K; Department of Respiratory Functional Exploration, University Medical Centre, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Nguyen-Mong G; Department of Sciences and Technology, Ho Chi Minh City, Binh Duong Province, Vietnam., Nguyen-Lan H; Intensive Care Unit of Covid 19, Binh Duong General Hospital, Ho Chi Minh City, Binh Duong Province, Vietnam., Vu-Van G; Respiratory Centre, Bach Mai Hospital, Hanoi City, Vietnam., Phan-Thu P; Respiratory Centre, Bach Mai Hospital, Hanoi City, Vietnam., Nguyen-Viet L; Department of Sciences and Technology, Ho Chi Minh City, Binh Duong Province, Vietnam., Nguyen-Hong C; Department of Health, Ho Chi Minh City, Binh Duong Province, Vietnam., Dinh-Ngoc S; Respiratory Department, National Hospital of Lung Diseases, Hanoi City, Vietnam., Nguyen-Duc T; Faculty of Health Sciences, Thang Long University, Hanoi City, Vietnam., Truong-Viet D; Faculty of Health Sciences, Thang Long University, Hanoi City, Vietnam., Vo-Pham-Minh T; Respiratory Department, Can Tho University of Medecine and Pharmacy, Can Tho Province, Vietnam., Le-Khac B; Phoi Viet Clinic, Ho Chi Minh City, Vietnam., Nguyen-Hong D; Phoi Viet Clinic, Ho Chi Minh City, Vietnam.; Department of Internal Medicine. School of Medicine, Tan Tao University, Đức Hòa, Long An Province, Vietnam., Craig T; Immuno-Allergology and Respiratory Department, Hershey Medical Center, Hershey, PA, USA., Nguyen-Nhu V; Department of Respiratory Functional Exploration, University Medical Centre, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. vinhnguyenmd@ump.edu.vn. |
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| Jazyk: | angličtina |
| Zdroj: | Pulmonary therapy [Pulm Ther] 2024 Dec; Vol. 10 (4), pp. 451-468. Date of Electronic Publication: 2024 Oct 18. |
| DOI: | 10.1007/s41030-024-00272-0 |
| Abstrakt: | Introduction: Most hospitalized patients required invasive or non-invasive ventilation and High Flow Nasal Cannula (HFNC). Therefore, this study was conducted to describe the characteristics of patients with severe Coronavirus Disease-2019 (COVID-19) treated by HFNC and its effectiveness for reducing the rate of intubated-mechanical ventilation in the Intensive Care Unit (ICU) of Phu Chanh COVID-19 Department-Binh Duong General Hospital. Methods: It was a cross-sectional and descriptive study. All severe patients with COVID-19 with acute respiratory failure eligible for the study were included. Patient characteristics, clinical symptoms, laboratory results, and treatment methods were collected for analysis; parameters and data related to HFNC treatment and follow-up were analysed. Results: 80 patients, aged of 49.7 ± 16.6 years, were treated with HFNC at admission in ICU. 14 patients had type 2 diabetes (17.5%), 3 patients had chronic respiratory disease (3.8%), 19 patients had high blood pressure (23.8%), and 5 patients with other comorbidities (7.4%). The majority of patients with severe COVID-19 had typical symptoms of COVID-19 such as shortness of breath (97.5%), intensive tired (81.3%), cough (73.7%), anosmia (48.3%), ageusia (41.3%), and fever (26.3%). The results of arterial blood gases demonstrated severe hypoxia under optimal conventional oxygen therapy (PaO Conclusion: HFNC therapy could be considered as a useful and effective alternative treatment for patients with acute respiratory failure. HFNC might help to delay the intubated ventilation for patients with respiratory failure and to minimise the risk of invasive ventilation complications and mortality. However, it is crucial to closely monitor the evolution of patient's respiratory status and responsiveness of HFNC treatment to avoid unintended delay of intubation-mechanical ventilation. Trial Registration: An independent ethics committee approved the study (The Ethics Committee of Binh Duong General Hospital; No. HDDD-BVDK BINH DUONG 9.2021), which was performed in accordance with the Declaration of Helsinki, Guidelines for Good Clinical Practice. Competing Interests: Declarations Conflict of Interest Sy Duong-Quy, Duc Huynh-Truong-Anh, Tram Tang-Thi-Thao, Thu Nguyen-Ngoc-Phuong, Phung Hoang-Phi-Tuyet, Anh Nguyen-Tuan, Toi Nguyen-Van, Thanh Nguyen-Chi, Thanh Nguyen-Thi-Kim, Tien Nguyen- Quang, Thuy Tran-Ngoc-Anh, Nam Nguyen-Van-Hoai, Mai Do-Thi-Thu, Huong Hoang-Thi-Xuan, Thai Nguyen-Duy, Cong Nguyen-Hai, Tuan Huynh-Anh, Quan Vu-Tran-Thien, Khue Bui-Diem, Giang Nguyen-Mong, Hieu Nguyen-Lan, Giap Vu-Van, Phuong Phan-Thu, Long Nguyen-Viet, Chuong Nguyen-Hong, Sy Dinh-Ngoc, Trong Nguyen-Duc, Dung Truong-Viet, Thu Vo-Pham-Minh, Bao Le-Khac, Duc Nguyen-Hong, Timothy Craig, Vinh Nguyen-Nhu have nothing to disclose. Sy Duong-Quy and Timothy Craig are Editorial Board members of PulmonaryTherapy. Sy Duong-Quy and Timothy Craig were not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. Ethical Approval This study was approved by the Ethics Committee of Binh Duong General Hospital (HDDD-BVDK BINH DUONG 9.2021). Written informed consent was obtained from the participants for the study and publication. The present study was performed in accordance with the Helsinki Declaration of 1964 and its later amendments. This study was conducted as a descriptive study and was not a randomized control trial. (© 2024. The Author(s).) |
| Databáze: | MEDLINE |
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