Immunological resilience of a temperate catshark to a simulated marine heatwave.

Autor:	Martins S; MARE - Marine and Environmental Sciences Centre/ARNET - Aquatic Research Network, Laboratório Marítimo da Guia, Faculdade de Ciências, Universidade de Lisboa, Portugal, 2750-374 Cascais, Portugal.; Comparative Molecular and Integrative Biology, Centro de Ciências do Mar, Universidade do Algarve, 8005-139 Faro, Portugal., Ferreira C; Instituto de Medicina Molecular, João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisbon, Portugal., Mateus AP; Comparative Molecular and Integrative Biology, Centro de Ciências do Mar, Universidade do Algarve, 8005-139 Faro, Portugal.; Escola Superior de Saúde, Universidade do Algarve, 8005-139 Faro, Portugal., Santos CP; MARE - Marine and Environmental Sciences Centre/ARNET - Aquatic Research Network, Laboratório Marítimo da Guia, Faculdade de Ciências, Universidade de Lisboa, Portugal, 2750-374 Cascais, Portugal., Fonseca J; Faculdade de Medicina Veterinária, Universidade Lusófona de Humanidades e Tecnologias (FMV-ULHT), 1749-024 Lisboa, Portugal., Rosa R; MARE - Marine and Environmental Sciences Centre/ARNET - Aquatic Research Network, Laboratório Marítimo da Guia, Faculdade de Ciências, Universidade de Lisboa, Portugal, 2750-374 Cascais, Portugal.; Departamento de Biologia Animal, Faculdade de Ciências, Universidade de Lisboa, Portugal, 1749-016 Cascais, Portugal.; Sphyrna Association, Boa Vista Island, Sal Rei, 5110, Cape Verde., Power DM; Comparative Molecular and Integrative Biology, Centro de Ciências do Mar, Universidade do Algarve, 8005-139 Faro, Portugal.
Jazyk:	angličtina
Zdroj:	The Journal of experimental biology [J Exp Biol] 2024 Nov 15; Vol. 227 (22). Date of Electronic Publication: 2024 Nov 20.
DOI:	10.1242/jeb.247684
Abstrakt:	Marine heatwaves (MHWs) have recently been proposed to be more relevant in driving population changes than the continuous increase in average temperatures associated with climate change. The causal processes underpinning MHW effects in sharks are unclear but may be linked to changes in fitness caused by physiological trade-offs that influence the immune response. Considering the scarcity of data about the immune response of sharks under anomalous warming events, the present study analyzed several fitness indices and characterized the immune response (in the blood, epigonal organ, liver, spleen and intestine) of temperate adult small-spotted catsharks (Scyliorhinus canicula) after a 30 day exposure to a category II MHW. The results indicated that adult small-spotted catsharks have developed coping strategies for MHWs. Specifically, among the 35 parameters investigated, only the gonad-to-body ratio (GBR) and plasma glucose concentration showed significant increases. In contrast, gene expression of igm and tumor necrosis factor receptor (tnfr) in blood cells, and tnfr in the epigonal organ, as well as the number of monocytes, all significantly decreased. Although a decline in immune function in small-spotted catsharks was revealed following MHW exposure, energy mobilization restored homeostasis and indicated a shift in energy allocation towards reproduction. Group resilience may be due to the variable tolerance of individuals, the phenotypic plasticity of cellular immunity, thermal imprinting and/or metabolic capacity of the individuals. Competing Interests: Competing interests The authors declare no competing or financial interests. (© 2024. Published by The Company of Biologists Ltd.)
Databáze:	MEDLINE
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