| Autor: |
Pan Q; School of Preclinical Medicine, Chengdu University, Chengdu 610106, China. panqingqing@cdu.edu.cn., Tang H; School of Preclinical Medicine, Chengdu University, Chengdu 610106, China. panqingqing@cdu.edu.cn., Xie L; School of Preclinical Medicine, Chengdu University, Chengdu 610106, China. panqingqing@cdu.edu.cn., Zhu H; School of Preclinical Medicine, Chengdu University, Chengdu 610106, China. panqingqing@cdu.edu.cn., Wu D; Meat Processing Key Laboratory of Sichuan Province, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China., Liu R; School of Preclinical Medicine, Chengdu University, Chengdu 610106, China. panqingqing@cdu.edu.cn., He B; National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Med-X Center for Materials, Sichuan University, Chengdu 610064, China. yjpu@scu.edu.cn., Pu Y; National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Med-X Center for Materials, Sichuan University, Chengdu 610064, China. yjpu@scu.edu.cn. |
| Abstrakt: |
Oral cancer is a significant global health challenge, with conventional treatments often resulting in substantial side effects and limited effectiveness. Phototherapy, encompassing photodynamic and photothermal therapy, presents a promising alternative by selectively targeting and destroying cancer cells with minimal systemic toxicity. However, issues such as insufficient light penetration and limited tumor specificity have restricted their clinical use. Recent advancements in nanosystems have addressed these challenges by enhancing the solubility, stability, and tumor-targeting capabilities of phototherapy agents. This review delves into the latest advancements in phototherapeutic nanosystems for oral cancer, focusing on the design of innovative nanoformulations and targeted delivery strategies. Additionally, it summarizes recent approaches to enhance the efficacy of photodynamic therapy for oral cancer and examines phototherapy-based combination treatments. These advancements hold the promise of significantly improving treatment outcomes while minimizing side effects in oral cancer therapy. |
