Effect of different CPAP levels on ultrasound-assessed lung aeration and gas exchange in neonates.
Autor: | Sartorius V; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France., Loi B; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France.; Physiopathology and Therapeutic Innovation Unit, Paris Saclay University, Paris, France., Vivalda L; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France., Regiroli G; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France.; Physiopathology and Therapeutic Innovation Unit, Paris Saclay University, Paris, France., De La Rubia-Ortega S; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France.; Physiopathology and Therapeutic Innovation Unit, Paris Saclay University, Paris, France., Pezza L; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France., Midevaine M; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France., Shankar-Aguilera S; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France., Ben-Ammar R; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France., De Luca D; Division of Pediatrics and Neonatal Critical Care, 'A. Béclère' Medical Center, Paris Saclay University Hospital, APHP - Paris, 157 rue de la Porte de Trivaux, Clamart, 92140, France. dm.deluca@icloud.com.; Physiopathology and Therapeutic Innovation Unit, Paris Saclay University, Paris, France. dm.deluca@icloud.com. |
---|---|
Jazyk: | angličtina |
Zdroj: | Respiratory research [Respir Res] 2024 Oct 17; Vol. 25 (1), pp. 375. Date of Electronic Publication: 2024 Oct 17. |
DOI: | 10.1186/s12931-024-03010-x |
Abstrakt: | Background: Respiratory distress syndrome (RDS) and transient tachypnoea (TTN) are the two commonest neonatal respiratory disorders. The optimal continuous positive airway pressure (CPAP) to treat them is unknown. We aim to clarify the effect of different CPAP levels on lung aeration and gas exchange in patients with RDS and TTN. Methods: Prospective, observational, pragmatic, physiological cohort study. CPAP was sequentially increased from 4 to 6 and 8 cmH Results: 30 neonates with RDS and 30 with TTN were studied. Each CPAP increment significantly (overall always p < 0.001) improved both lung aeration and oxygenation, but the increase from 6 to 8 cmH Conclusions: Increasing CPAP from 4 to 8 cmH (© 2024. The Author(s).) |
Databáze: | MEDLINE |
Externí odkaz: | |
Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |