Multimodal ultrasound assessment of mass and non-mass enhancements by MRI: Diagnostic accuracy in idiopathic granulomatous mastitis and breast cancer.

Autor: Yin L; Department of Breast Surgery, Jiangsu University Affiliated People's Hospital, Zhenjiang, China; Zhenjiang Clinical Medical College of Nanjing Medical University, Zhenjiang, China., Wei X; Department of Pathology, Jiangsu University Affiliated People's Hospital, Zhenjiang, China., Zhang Q; Department of Ultrasound, Jiangsu University Affiliated People's Hospital, Zhenjiang, China., Xiang L; Department of Radiology, Jiangsu University Affiliated People's Hospital, Zhenjiang, China., Zhang Y; Department of Radiology, Jiangsu University Affiliated People's Hospital, Zhenjiang, China., Wang D; Department of Breast Surgery, Jiangsu University Affiliated People's Hospital, Zhenjiang, China., Chen P; Department of Breast Surgery, Jiangsu University Affiliated People's Hospital, Zhenjiang, China., Cao X; Department of Breast Surgery, Jiangsu University Affiliated People's Hospital, Zhenjiang, China., Shaibu Z; School of Medicine, Jiangsu University, Zhenjiang, China., Qin R; Department of Medical Oncology, Jiangsu University Affiliated People's Hospital, Zhenjiang, China; Zhenjiang Clinical Medical College of Nanjing Medical University, Zhenjiang, China. Electronic address: jiangsu.qinrong@163.com.
Jazyk: angličtina
Zdroj: Breast (Edinburgh, Scotland) [Breast] 2024 Dec; Vol. 78, pp. 103797. Date of Electronic Publication: 2024 Sep 12.
DOI: 10.1016/j.breast.2024.103797
Abstrakt: Purpose: Idiopathic granulomatous mastitis (IGM) poses diagnostic challenges due to its diverse clinical and radiological presentations, often mimicking malignancies. This study aimed to assess the diagnostic efficacy of multimodal ultrasound for mass and non-mass enhancements in Dynamic Contrast-Enhanced MRI (DCE-MRI) of IGM and breast cancer.
Methods: A retrospective analysis involved patients confirmed histopathologically with IGM and BC. All patients underwent conventional ultrasound (C-US), ultrasound elastography (UE), contrast-enhanced ultrasound (CEUS), and DCE-MRI examinations. Blinded experienced radiologists assessed imaging findings. Diagnostic accuracy, sensitivity, and specificity were calculated for mass and non-mass enhancements.
Results: For mass enhancements (ME), multimodal ultrasound demonstrated strong efficacy (AUC = 0.8651, 95 % CI: 0.7431 to 0.9871), exhibiting high sensitivity (83.3 %) and specificity (92.4 %) in differentiating IGM from breast cancer. However, for non-mass enhancements (NME), multimodal ultrasound showed limited accuracy (AUC = 0.6306) with lower sensitivity (65.6 %) and specificity (81.2 %) in distinguishing between IGM and breast cancer.
Conclusion: Multimodal ultrasound displayed good diagnostic efficacy for mass enhancements in DCE-MRI for IGM and breast cancer, while for non-mass enhancement patterns, DCE-MRI remains the most valuable radiological modality for comprehensively assessing this condition's complexities.
Competing Interests: Declaration of competing interests The authors declare that they have no competing interests.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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