S3 guideline: Diagnosis and treatment of epidermal necrolysis (Stevens-Johnson syndrome and toxic epidermal necrolysis) - Part 2: Supportive therapy of EN in the acute and post-acute stages.

Autor: Paulmann M; Department of Dermatology and Venereology, Center for the Documentation of Severe Skin Reactions (dZh), University Medical Center Freiburg, Freiburg, Germany., Heuer R; Department of Dermatology, Venereology and Allergology, Division of Evidence Based Medicine (dEBM), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Annecke T; Department of Anesthesiology and Critical Care Medicine, Merheim Medical Center, Hospital of Witten/Herdecke University, Cologne, Germany., Behr B; Department of Plastic and Hand Surgery, Burn Center, Sarcoma Center, BG University Hospital Bergmannsheil, Ruhr University Bochum, Bochum, Germany.; Department of Plastic, Reconstructive & Aesthetic Surgery, KEM Evangelische Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung Essen-Huttrop, Essen, Germany., Boch K; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Lübeck, Germany., Boos AM; Department of Plastic Surgery, Hand Surgery - Burn Center, University Hospital RWTH Aachen, Aachen, Germany., Brockow K; Department of Dermatology and Allergology, University Medical Center, Technical University of Munich, Munich, Germany., French LE; Department of Dermatology and Allergy, Ludwig Maximilian University Munich, Munich, Germany., Gille J; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, St. Georg Hospital Leipzig, Leipzig, Germany., Gundlach V; Heart Center Niederrhein - Department of Cardiac Surgery and Cardiovascular Surgery, Helios Hospital Krefeld, Krefeld, Germany., Hartmann B; Department of Plastic Surgery, Burn Centre, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany., Höger P; Department of Pediatric Dermatology/Allergology, Catholic Children's Hospital Wilhelmstift Hamburg, Hamburg, Germany., Hofmann SC; Center for Dermatology, Allergology and Dermatosurgery, Helios University Hospital Wuppertal, University of Witten/Herdecke, Wuppertal, Germany., Klein T; Department of Pediatric Surgery and Pediatric Urology, Children's Hospital of Cologne, Cologne, Germany., Lehnhardt M; Department of Plastic and Hand Surgery, Burn Center, Sarcoma Center, BG University Hospital Bergmannsheil, Ruhr University Bochum, Bochum, Germany., Liß Y; Office Dr. Jana Filser, Mannheim, Germany., Maier P; Eye Center, University Medical Center Freiburg, Freiburg, Germany., Mandel P; Department of Urology, University Hospital Frankfurt, Frankfurt am Main, Germany., Marathovouniotis N; Department of Pediatric Surgery and Pediatric Urology, Children's Hospital of Cologne, Cologne, Germany., Marlok F; Patient Representative, Untermünkheim, Germany., Mittelviefhaus H; Department of Dermatology and Allergy, Ludwig Maximilian University Munich, Munich, Germany., Pleyer U; Department of Ophthalmology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Pradeau M; Department of Dermatology, Venereology and Allergology, Division of Evidence Based Medicine (dEBM), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Rall K; Department of Women's Health, University Hospital Tübingen, Tübingen, Germany., Rieg S; Department of Medicine II - Gastroenterology, Hepatology, Endocrinology and Infectiology, University Medical Center Freiburg, Freiburg, Germany., Rittner H; Department of Anesthesiology, Intensive Care, Emergency and Pain Medicine, Centre for Interdisciplinary Pain Medicine, University Hospital Würzburg, Würzburg, Germany., Sander F; Department of Plastic Surgery, Burn Centre, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany., Schnitzler S; Department of Surgical Intensive Care and Intermediate Care, University Hospital RWTH Aachen, Aachen, Germany., Schut C; Institute of Medical Psychology, Justus Liebig University Gießen, Gießen, Germany., Stolle A; Andreas Wentzensen Research Institute, BG Hospital Ludwigshafen, Ludwigshafen, Germany., Vorobyev A; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Lübeck, Germany., Wedi B; Department of Dermatology, Allergology and Venereology, Hannover Medical School, Hannover, Germany., Weiss J; Department of Dermatology and Allergology, University Hospital Ulm, Ulm, Germany., Zepp M; Patient Representative, Kaiserslautern, Germany., Ziemer M; Department of Dermatology, Venereology and Allergology, University Hospital Leipzig, Leipzig, Germany., Mockenhaupt M; Department of Dermatology and Venereology, Center for the Documentation of Severe Skin Reactions (dZh), University Medical Center Freiburg, Freiburg, Germany., Nast A; Department of Dermatology, Venereology and Allergology, Division of Evidence Based Medicine (dEBM), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Jazyk: angličtina
Zdroj: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG [J Dtsch Dermatol Ges] 2024 Nov; Vol. 22 (11), pp. 1576-1593. Date of Electronic Publication: 2024 Oct 17.
DOI: 10.1111/ddg.15516
Abstrakt: Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are rare, predominantly drug-induced, acute life-threatening diseases of skin and mucosae. SJS and TEN are nowadays considered as variants of one disease entity with varying degrees of severity called epidermal necrolysis (EN). EN is associated with high morbidity and mortality and constitutes a major disease burden for affected patients. The guideline "Diagnosis and treatment of epidermal necrolysis (Stevens-Johnson syndrome and toxic epidermal necrolysis)" was developed under systematic consideration of existing scientific literature and in a formal consensus process according to regulations issued by the Association of Scientific Medical Societies in Germany (AWMF) to establish an evidence-based framework to support clinical decision-making. The interdisciplinary guideline commission consisted of representatives from various specialist societies and of patient representatives. The guideline is aimed at specialists in the fields of dermatology, ophthalmology, plastic surgery, intensive care, and pediatrics in hospitals and offices, as well as other medical specialties involved in the diagnosis and treatment of EN. The guideline is also aimed at patients, their relatives, insurance funds, and policymakers. The second part is concerned with the topics of supportive therapy in the acute phase of EN and outpatient follow-up treatment.
(© 2024 The Author(s). Journal der Deutschen Dermatologischen Gesellschaft published by Wiley‐VCH GmbH on behalf of Deutsche Dermatologische Gesellschaft.)
Databáze: MEDLINE
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