Vaccination significantly reduced the length of SARS-CoV-2 viral clearance: A story from international healthcare workers.

Autor:	Wang HB; Zhuhai International Travel Healthcare Center, Zhuhai, Guangdong, China., Cheng ZD; Zhuhai International Travel Healthcare Center, Zhuhai, Guangdong, China., Chen XB; Zhuhai International Travel Healthcare Center, Zhuhai, Guangdong, China., Huang HN; Zhuhai International Travel Healthcare Center, Zhuhai, Guangdong, China., Liao MH; Zhuhai International Travel Healthcare Center, Zhuhai, Guangdong, China.
Jazyk:	angličtina
Zdroj:	Journal of investigative medicine : the official publication of the American Federation for Clinical Research [J Investig Med] 2024 Oct 29, pp. 10815589241296028. Date of Electronic Publication: 2024 Oct 29.
DOI:	10.1177/10815589241296028
Abstrakt:	To investigate the impact of vaccines on sociodemographic characteristics, clinical profiles, and outcomes of SARS-CoV-2 infection among healthcare workers in South China during the period of Omicron variant dominance, a retrospective, analytical cross-sectional study was conducted. The findings revealed that while full vaccination could not prevent Omicron variant infection efficiently (26.51% uninfected vs 14.29% uninfected between vaccinated and unvaccinated participants, p = 0.506), it did substantially reduce the length of viral clearance significantly (p < 0.05), potentially facilitating quicker patient recovery. Unvaccination was found to be an independent risk factor for slow clearance when a linear regression analysis model was used (Coefficient: -3.516; 95% CI: -6.425 to -0.607; p = 0.020). Therefore, all eligible individuals should be fully vaccinated to get prepared for a potential wave of epidemic in the future. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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