A SynBio community comes of age: Political, academical, industrial, and societal developments in the Netherlands.

Autor:	Bhatt DK; Department of Medical Microbiology and Infection Prevention, University Medical Center Groningen, University of Groningen, the Netherlands., Crooijmans ME; Microbial Sciences, Institute of Biology Leiden, Leiden University, Leiden, the Netherlands., Coenradij J; Department of Biochemistry, Groningen Institute of Biomolecular Sciences & Biotechnology, University of Groningen, the Netherlands., Maciá Valero A; Department of Molecular Microbiology, University of Groningen, Groningen, the Netherlands., Lubbers M; Microbial Sciences, Institute of Biology Leiden, Leiden University, Leiden, the Netherlands., Asin-Garcia E; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, the Netherlands., Yewdall NA; Institute for Molecules and Materials, Faculty of Science, Radboud University, Nijmegen, the Netherlands., D'Adamo S; Bioprocess Engineering, Wageningen University, Wageningen, the Netherlands., Claassens NJ; Laboratory of Microbiology, Wageningen University, Wageningen, the Netherlands., Billerbeck S; Department of Molecular Microbiology, University of Groningen, Groningen, the Netherlands.
Jazyk:	angličtina
Zdroj:	Biotechnology notes (Amsterdam, Netherlands) [Biotechnol Notes] 2022 Aug 06; Vol. 3, pp. 62-69. Date of Electronic Publication: 2022 Aug 06 (Print Publication: 2022).
DOI:	10.1016/j.biotno.2022.07.004
Abstrakt:	Synthetic biology (SynBio) is a rapidly growing scientific discipline. In the Netherlands, various universities and companies are tackling a variety of opportunities and challenges within this field. In this perspective article, we review the current synthetic biology landscape in the Netherlands across academia, industry, politics, and society. Especially within Dutch academia there is an active, though only partially connected, research community involved in various domains of SynBio. Mostly supported by governmental funding, academic research is focusing on top-down synthetic biology, involving the engineering of, for example, bacteria and yeast for bioproduction, as well as bottom-up and cell-free synthetic biology aiming to understand life and build synthetic cells. There is also a large number of talented and motivated students interested in the field, exemplified by the participation and success of Dutch teams in the international iGEM synthetic biology competition. Commercial synthetic biology activities are taking place in various large industrial companies, as well as in start-ups and spin-offs, mostly divided over several 'SynBio hubs' in the Netherlands. However, the investment, regulatory and public-perception landscape is not yet optimal to stimulate entrepreneurial activities in SynBio. The Dutch and global society can further benefit from the large promise of SynBio through better integration of people active in the Dutch SynBio field, frequent political and public dialogue, and more attention towards regulatory issues. The recently founded Dutch synthetic biology association SynBioNL aims to contribute to realizing a positive impact on society by stimulating advances of the field in the Netherlands and beyond. Competing Interests: The authors have no conflicts of interest to disclose. (© 2022 The Authors.)
Databáze:	MEDLINE
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