Elephant endotheliotropic herpesvirus gB-specific antibody levels in sera of Asian elephants (Elephas maximus) in Japanese zoos.

Autor: Takehana K; Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.; Ichihara Elephant Kingdom Zoological Park, Chiba, Japan., Hoornweg TE; Section Virology, Division Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, CL Utrecht, The Netherlands.; Section Immunology, Division Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, CL Utrecht, The Netherlands., Schaftenaar W; Veterinary Advisor EAZA Elephant TAG, Rotterdam Zoo, JG Rotterdam, The Netherlands., Rutten VP; Section Immunology, Division Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, CL Utrecht, The Netherlands.; Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa., DE Haan CA; Section Virology, Division Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, CL Utrecht, The Netherlands., Matsuno K; Division of Risk Analysis and Management, International Institute for Zoonosis Control, Hokkaido University, Hokkaido, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Hokkaido, Japan.; One Health Research Center, Hokkaido University, Hokkaido, Japan.; Institute for Vaccine Research and Development: HU-IVReD, Hokkaido University, Hokkaido, Japan.
Jazyk: angličtina
Zdroj: The Journal of veterinary medical science [J Vet Med Sci] 2024 Dec 01; Vol. 86 (12), pp. 1279-1283. Date of Electronic Publication: 2024 Oct 16.
DOI: 10.1292/jvms.23-0503
Abstrakt: Prevalence of elephant endotheliotropic herpesvirus (EEHV) infections in Asian elephants in Japan was assessed by determination of EEHV gB specific antibody levels. Among 28 healthy Asian (sub) adult elephants from 11 zoos, 27 animals exhibited intermediate to high antibody levels. Like elsewhere worldwide, this suggested exposure of Asian elephants in Japan to at least one EEHV (sub) species. Longitudinal observations of two elephants monitored from birth to 30-month of age showed consistent high antibody levels. Another juvenile showed antibody levels that decreased to undetectable levels prior to death at 13 months of age. This fatal case supports earlier reports that low antibody levels are a risk factor for development of EEHV hemorrhagic disease.
Databáze: MEDLINE