Validation of a Simplified Laboratory-Based HCV Clearance Definition Using New York City Hepatitis C Program and Surveillance Data.
| Autor: | Hwang CS; Author Affiliations: Bureau of Hepatitis, HIV and STI, New York City Department of Health and Mental Hygiene, New York City, New York (Mss Hwang, Diaz Munoz, and Bocour); and National Center for HIV, Viral Hepatitis, STD, and TB Prevention at US Centers for Disease Control and Prevention, Atlanta, Georgia (Drs Montgomery, Yin, and Teshale)., Montgomery MP, Diaz Munoz DI, Yin S, Teshale EH, Bocour A |
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| Jazyk: | angličtina |
| Zdroj: | Journal of public health management and practice : JPHMP [J Public Health Manag Pract] 2024 Oct 16. Date of Electronic Publication: 2024 Oct 16. |
| DOI: | 10.1097/PHH.0000000000002077 |
| Abstrakt: | Context: Laboratory-based hepatitis C virus (HCV) clearance cascades are an important tool for health departments to track progress toward HCV elimination, but a laboratory-based definition of HCV clearance has not yet been validated. Objective: To compare agreement between a laboratory-based HCV clearance definition with a clinical cure definition. Design: Observational. Setting: New York City Department of Health and Mental Hygiene HCV surveillance system data and New York City hepatitis C linkage-to-care program data. Participants: Linkage-to-care program participants who were diagnosed with hepatitis C and enrolled in the linkage-to-care program from July 1, 2016, through June 30, 2020. Main Outcome Measure: Percent agreement between a laboratory-based HCV clearance definition (surveillance system) and a clinical cure definition (program data). Results: Among 591 program participants with known treatment outcome, the laboratory-based HCV clearance definition and clinical cure definition were concordant in 573 cases (97%). Conclusions: A laboratory-based HCV clearance definition based on public health surveillance data can be a reliable source for monitoring HCV elimination. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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