A Systematic Review of the Impact of Dietary and Lifestyle Factors on Colorectal Cancer Prevention in Gulf Cooperation Council Countries.

Autor:	Rashed Adam T; Dental Health, College of Applied Medical Sciences, King Saud University, Riyadh, SAU., Bakhamees BH; Medicine, King Abdulaziz University, Jeddah, SAU., Abdulla Ali Ahmed Ali M; Internal Medicine, Al Jenan Medical Center, A'ali, BHR., Hamed AM; Stroke, United Lincolnshire Hospital Trust, Lincolnshire, GBR., Alotaibi A; Medicine, Taif University, Taif, SAU., Mohamed Hamato A; Internal Medicine, Shifa Rahima Medical Complex, Ras Tanura, SAU., Taha Zatari R; Family Medicine, Riyadh Second Health Cluster, Riyadh, SAU., Abdulmalik Fahad S; Medical Sciences, Ibn Sina National College for Medical Sciences, Jeddah, SAU., Abdulaziz Abdulbari R; Neurology, King Salman Bin Abdulaziz Medical City Madinah Hospital, Al Madinah Al Munawwarah, SAU., Marzooq Alharbi H; Family Medicine, Urwa Health Care Center, Al Madinah Al Munawwarah, SAU., Abdelbaky M; Neonatology, Prince Sultan Military Medical City, Riyadh, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Sep 15; Vol. 16 (9), pp. e69439. Date of Electronic Publication: 2024 Sep 15 (Print Publication: 2024).
DOI:	10.7759/cureus.69439
Abstrakt:	Colorectal cancer (CRC) remains a significant health burden in the Gulf Cooperation Council (GCC) countries, necessitating a deeper understanding of modifiable risk factors. Thus, the aim of the study was to evaluate the impact of dietary and lifestyle factors on the prevention of CRC in GCC countries. Studies were identified through electronic searches and reviewed based on relevant keywords. Databases searched included Ovid's MEDLINE, EMBASE, Google Scholar, and Web of Science, covering titles and abstracts published between January 1, 2000 and July 25, 2024. The search strategy encompassed four thematic areas: "colorectal cancer," "adults above 18," "risk factors," and "GCC countries." The primary focus was on dietary and lifestyle factors. Two reviewers screened titles and abstracts to determine whether the inclusion criteria were met. A total of 1,883 records were identified across these databases. After removing 513 duplicate records, 1,370 records were screened based on titles and abstracts. Of these, 1,284 records were excluded, leaving 86 full-text articles for assessment. Eight studies were ultimately included in the final systematic review, consisting of seven case-control studies and one cross-sectional study. In GCC countries, a diet rich in fruits, vegetables, and fiber has shown protective effects against CRC, while high red meat and refined carbohydrate intake may increase risk. Regular physical activity reduces CRC risk, though the impact of smoking remains inconclusive. Evidence regarding dairy products is contradictory. There is a shortage of high-quality longitudinal studies, highlighting gaps in current research and underscoring the need for larger studies with consistent methodologies. Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Rashed Adam et al.)
Databáze:	MEDLINE
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