Evaluation of Peri-Operative Outcomes after Prostatic Urethral Lift with Emphasis on Urodynamic Changes, Symptom Improvement and Sexual Function.

Autor: Lombardo R; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Santarelli V; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Turchi B; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Santoro G; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Guercio A; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Franco A; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Secco S; Department of Urology, Ospedale Niguarda, 20162 Milan, Italy., Dell'Oglio P; Department of Urology, Ospedale Niguarda, 20162 Milan, Italy., Galfano A; Department of Urology, Ospedale Niguarda, 20162 Milan, Italy., Olivero A; Department of Urology, Ospedale Niguarda, 20162 Milan, Italy., Pastore AL; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Al Salhi Y; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Fuschi A; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Nacchia A; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Tema G; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Fegiz A; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Fusco F; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Cini R; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Cicione A; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., Tubaro A; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy., De Nunzio C; Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2024 Sep 24; Vol. 14 (19). Date of Electronic Publication: 2024 Sep 24.
DOI: 10.3390/diagnostics14192110
Abstrakt: Background and Aims: The aim of our study is to evaluate the possible urodynamic effect of prostatic urethral lift (PUL) in patients with lower urinary tract symptoms due to benign prostatic hyperplasia. Methods : A consecutive series of patients undergoing PUL placement were consecutively enrolled in two centers. Inclusion criteria: ≥50 years of age, benign prostatic obstruction (BPO), international prostate symptom score (IPSS) ≥ 13, prostate volume ≤ 60 mL, and no middle prostate lobe. All patients were evaluated using a detailed clinical history, a validated questionnaire, flexible cystoscopy, and pressure flow studies (PFS) at baseline. PFS were performed at 6 months to evaluate the urodynamic effect of PUL. Results : Overall, 20 patients with a median age of 63 were enrolled. At six months, statistically significant improvements in terms of median Qmax (11.5 vs. 8.5; p < 0.05) and median IPSS (16 vs. 10.5; p < 0.05) were recorded, and sexual function was maintained. All urodynamic parameters improved at 6 months, and significance was reached for all values except for PdetQmax. Finally, Schäfer's class improved from a median of III to a median of II. More specifically, 16/20 presented an improvement in the Schäfer class, and 12/20 patients presented a BOOI < 20 at 6 months. Conclusions: PUL represents an effective treatment in patients with LUTS due to BPH and improves bladder outlet obstruction without any effect on sexual function.
Databáze: MEDLINE
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