Adverse Childhood Events Significantly Impact Depression and Mental Distress in Adults with a History of Cancer.

Autor: Babatunde OA; Department of Psychiatry, Prisma Health, Greer, SC 29650, USA., Gonzalez K; School of Medicine, California University of Science and Medicine, Colton, CA 92324, USA.; Department of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, NC 27710, USA., Osazuwa-Peters N; Department of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Cancer Institute, Durham, NC 27701, USA., Adams SA; Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, 915 Greene Street, Columbia, SC 29208, USA.; Biobehavioral Health and Nursing Science Department, College of Nursing, University of South Carolina, 1601 Greene Street, Columbia, SC 29208, USA., Hughes Halbert C; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA 90032, USA.; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA., Clark F; Department of Psychiatry, Prisma Health, Greer, SC 29650, USA.; School of Medicine-Greenville, University of South Carolina, Greenville, SC 29605, USA., Nagar A; Department of Psychiatry, Prisma Health, Greer, SC 29650, USA.; School of Medicine-Greenville, University of South Carolina, Greenville, SC 29605, USA., Obeysekare J; Department of Psychiatry, Prisma Health, Greer, SC 29650, USA.; School of Medicine-Greenville, University of South Carolina, Greenville, SC 29605, USA., Adjei Boakye E; Department of Public Health Sciences, Henry Ford Health System, Detroit, MI 48202, USA.; Department of Otolaryngology-Head and Neck Surgery, Henry Ford Health System, Detroit, MI 48202, USA.; Henry Ford Health + Michigan State University Health Sciences, Detroit, MI 48202, USA.; Department of Epidemiology and Biostatistics, Michigan State University College of Human Medicine, East Lansing, MI 48824, USA.
Jazyk: angličtina
Zdroj: Cancers [Cancers (Basel)] 2024 Sep 27; Vol. 16 (19). Date of Electronic Publication: 2024 Sep 27.
DOI: 10.3390/cancers16193290
Abstrakt: Objectives: Adverse childhood experiences (ACEs) are linked to a heightened risk of depression. We explored the relationship between ACEs and both depression and mental distress among cancer survivors. Methods: This was a cross-sectional analysis using the 2022 Behavioral Risk Factor Surveillance System database of cancer survivors aged ≥18 (n = 14,132). The primary outcome was self-reported history of depression, and the secondary outcome was mental distress. The exposure variable was the number of ACEs, classified as 0, 1-2, and ≥3. Weighted multivariable logistic regression models assessed the association between the number of ACEs and depression and mental distress while adjusting for covariates. Results: Approximately 22% of respondents reported experiencing ≥3 ACEs. The prevalence of depression was 21.8%, and mental distress was 15.4%. Compared with cancer survivors who had experienced 0 ACEs, those who had experienced ≥3 (aOR = 3.94; 95% CI, 3.04-5.10) or 1-2 (aOR = 1.85; 95% CI, 1.47-2.32) ACEs had a higher likelihood of reporting depression. Compared with cancer survivors who had experienced 0 ACEs, those who had experienced ≥3 (aOR = 0.67; 95% CI, 0.48-0.93) had a lower likelihood of reporting mental distress. Conclusions: This study highlights the impact of ACEs on depression in adulthood among cancer survivors.
Databáze: MEDLINE
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