Bone Marrow and Metabolic Bone Disease.
| Autor: | Aparisi Gómez MP; Department of Radiology, Te Toka Tumai Auckland (Auckland District Health Board), Grafton, Auckland, New Zealand.; Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Department of Radiology, IMSKE, València, Spain., Bazzocchi A; Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. |
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| Jazyk: | angličtina |
| Zdroj: | Seminars in musculoskeletal radiology [Semin Musculoskelet Radiol] 2024 Oct; Vol. 28 (5), pp. 515-527. Date of Electronic Publication: 2024 Oct 15. |
| DOI: | 10.1055/s-0044-1788692 |
| Abstrakt: | The bone marrow represents one of the largest organs in the body, with a relevant metabolic role that continues to be investigated. Numerous studies have focused on marrow adipose tissue (MAT). Evidence indicates that the bone marrow adipocytes do not only work as storage tissue but also consist of endocrine and paracrine cells, with the potential to contribute to local and systemic metabolism. MAT plays a role in bone health through its interaction with the other components of bone. Many metabolic disorders (osteoporosis, obesity, diabetes) have a complex and still not well-established or understood relationship with bone health. This article surveys the literature on the relationship of bone marrow and metabolic disorders, and how it is being studied using imaging techniques, with a special focus on bone health. Competing Interests: None declared. (Thieme. All rights reserved.) |
| Databáze: | MEDLINE |
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