Interaction of topical and oral timolol in glaucoma.

Autor: Batchelor ED, O'Day DM, Shand DG, Wood AJ
Jazyk: angličtina
Zdroj: Ophthalmology [Ophthalmology] 1979 Jan; Vol. 86 (1), pp. 60-5.
DOI: 10.1016/s0161-6420(79)35544-0
Abstrakt: The interaction of oral and topical timolol maleate was studied in patients with open-angle glaucoma. The oral and topical preparations given separately produced a significant and comparable reduction of the intraocular pressure, but no additive effect was observed when both preparations were given together. Pulse- and blood pressure-lowering effects of oral timolol were not enhanced by the application of topical timolol. These systemic effects were not found in those patients using topical timolol alone.
Databáze: MEDLINE