Fluorescent polymers for environmental monitoring: Targeting pathogens and metal contaminants with naphthalimide derivatives.

Autor: Galhano J; BIOSCOPE Research Group, LAQV-REQUIMTE, Chemistry Department, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica 2829-516, Portugal., Kurutos A; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev str., bl. 9, Sofia 1113, Bulgaria; University of Chemical Technology and Metallurgy, 8 St. Kliment Ohridski blvd, Sofia 1756, Bulgaria. Electronic address: Atanas.Kurutos@orgchm.bas.bg., Dobrikov GM; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev str., bl. 9, Sofia 1113, Bulgaria., Duarte MP; MEtRICs / NOVA School of Science and Technology, Universidade NOVA de Lisboa, Campus de Caparica, Caparica 2829-516, Portugal., Santos HM; PROTEOMASS Scientific Society, Costa da Caparica 2825-466, Portugal., Capelo-Martínez JL; PROTEOMASS Scientific Society, Costa da Caparica 2825-466, Portugal., Lodeiro C; PROTEOMASS Scientific Society, Costa da Caparica 2825-466, Portugal. Electronic address: cle@fct.unl.pt., Oliveira E; PROTEOMASS Scientific Society, Costa da Caparica 2825-466, Portugal. Electronic address: ej.oliveira@fct.unl.pt.
Jazyk: angličtina
Zdroj: Journal of hazardous materials [J Hazard Mater] 2024 Dec 05; Vol. 480, pp. 136107. Date of Electronic Publication: 2024 Oct 09.
DOI: 10.1016/j.jhazmat.2024.136107
Abstrakt: Monitoring Hg 2+ levels in aqueous environments is crucial to assess the potential methylmercury contamination via bacterial conversion, however, existing methods often require extensive sample treatment and expensive equipment. To mitigate this issue, this study examines the synthesis and application of three naphthalimide-based compounds, with significant fluorescent and solvatochromic behavior (C1, C2, and C3). Compounds C1 and C2 demonstrated a strong affinity for Hg 2+ metal ions, with C2 showing selectivity and a strong antibacterial profile, particularly against S. aureus (MIC 50 (C2) = 0.01 µg/mL). Moreover, these compounds were incorporated into three polymeric matrices, namely polyvinyl chloride (PVC), poly (methyl methacrylate-co-methacrylic acid) (PMMMA), and Starch, allowing for the development of solid-support sensors/surfaces with a strong antibacterial profile, highlighting the inherent dual-functionality of the compounds. Interestingly, the C2-doped Starch biopolymer detected low concentrations of Hg 2+ ions, such as 23 nM in tap water (value within the WHO standards for drinking water), through a rapid spectroscopic evaluation without sample treatment. This biopolymer was generated via a sustainable, green-chemistry-oriented, temperature-dependent water/Starch synthetic route, without the addition of plasticizers and any associated ecotoxicity. The study used sustainable methods for environmental monitoring and antibacterial applications, advancing material science to offer effective, accessible, and eco-friendly solutions for detecting and mitigating mercury pollution and bacterial contaminations, enhancing environmental and health safety.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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