Association of Vitamin D and magnesium levels with severity and mortality in patients with COVID-19.
| Autor: | García-Zendejas MM; Servicio de Urgencias, Hospital General Salvador Zubirán Anchondo, Chihuahua, Chihuahua., Cano-Torres EA; Department of Internal Medicine, Hospital Rebren, Durango, Durango., Simental-Mendía LE; Unidad de Investigación Biomédica, Delegación Durango, Instituto Mexicano del Seguro Social, Durango, Durango. México. |
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| Jazyk: | angličtina |
| Zdroj: | Cirugia y cirujanos [Cir Cir] 2024; Vol. 92 (5), pp. 603-607. |
| DOI: | 10.24875/CIRU.23000514 |
| Abstrakt: | Objective: The study aimed to determine the association between serum magnesium and Vitamin D levels with the severity and mortality by coronavirus disease 19 (COVID-19) in hospitalized patients. Method: Men and women over 18 years of age with probable COVID-19 were enrolled in a case-control study. Patients with a positive or negative test for Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were allocated into case or control groups, respectively. Vitamin D deficiency was defined by concentrations < 20 ng/mL and hypomagnesemia by serum levels < 1.8 mg/dL. Results: A total of 54 patients, 30 women and 24 men, were enrolled and allocated into the groups with (n = 27) and without (n = 27) COVID-19. The logistic regression analysis showed that Vitamin D deficiency (odds ratio [OR] = 6.13; 95% confidence intervals [CI]: 1.32-28.34) and insufficiency (OR = 0.12; 95% CI: 0.02-0.60) are significantly associated with hospitalization. However, Vitamin D disorders and hypomagnesemia were not associated with mortality. Conclusions: The results of the present study revealed that Vitamin D disturbances, but not hypomagnesemia, are associated with the severity of SARS-CoV-2. (Copyright: © 2024 Permanyer.) |
| Databáze: | MEDLINE |
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