Successful Use of Fecal Microbiota Transplantation in Management of Nonobstructive Recurrent Cholangitis Following Total Pancreatectomy and Islet Autotransplant.
| Autor: | Scott A; University of Minnesota Medical School, Minneapolis, MN., Khoruts A; University of Minnesota Medical Center, Minneapolis, MN., Freeman ML; University of Minnesota Medical Center, Minneapolis, MN., Beilman G; University of Minnesota Medical Center, Minneapolis, MN., Ramanathan K; University of Minnesota Medical Center, Minneapolis, MN., Bellin MD; University of Minnesota Medical Center, Minneapolis, MN., Trikudanathan G; University of Minnesota Medical Center, Minneapolis, MN. |
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| Jazyk: | angličtina |
| Zdroj: | ACG case reports journal [ACG Case Rep J] 2024 Oct 11; Vol. 11 (10), pp. e01527. Date of Electronic Publication: 2024 Oct 11 (Print Publication: 2024). |
| DOI: | 10.14309/crj.0000000000001527 |
| Abstrakt: | Alterations in the gut microbiome have been implicated in various pathologies. Fecal microbiota transplantation (FMT) has been offered as a novel treatment for conditions implicated in the disruption of the gut-microbiota axis. This case report details the successful treatment of recurrent nonobstructive cholangitis following a single FMT application in a patient who had previously undergone a hepatobiliary tract surgical diversion. Cholangitis was suspected secondary to reflux of an altered microbiome into the surgically reanastomosed biliary tract, and FMT was justified based on the history of recurrent Clostridioides difficile infections. This case supports the further evaluation of the utility of FMT as one potential treatment of post hepatobiliary surgical diversion cholangitis. (© 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.) |
| Databáze: | MEDLINE |
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