A case of gastritis caused by immune checkpoint inhibitor treated with infliximab.

Autor: Itsukage S; Department of Dermatology, Kansai Medical University Hospital, 2-5-1 Shinmachi, Hirakata City, Osaka Japan., Kume N; Department of Dermatology, Kansai Medical University Hospital, 2-5-1 Shinmachi, Hirakata City, Osaka Japan., Tajima A; Department of Dermatology, Kansai Medical University Hospital, 2-5-1 Shinmachi, Hirakata City, Osaka Japan., Okazaki T; Third Department of Internal Medicine, Kansai Medical University Hospital, Hirakata City, Japan., Tsuta K; Department of Pathology, Kansai Medical University Hospital, Hirakata City, Japan., Tanizaki H; Department of Dermatology, Kansai Medical University Hospital, 2-5-1 Shinmachi, Hirakata City, Osaka Japan.
Jazyk: angličtina
Zdroj: International cancer conference journal [Int Cancer Conf J] 2024 Sep 18; Vol. 13 (4), pp. 454-459. Date of Electronic Publication: 2024 Sep 18 (Print Publication: 2024).
DOI: 10.1007/s13691-024-00709-y
Abstrakt: Immune checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs) in various organs. Herein, we present a rare case involving a patient with immunotherapy-related gastritis who developed refractory vomiting and anorexia after treatment with nivolumab for cutaneous malignant melanoma. The patient was treated with oral corticosteroids, but the efficacy was limited. The symptoms improved markedly after treatment with infliximab. With the increasing use of ICIs, the number of reports of gastritis due to irAEs has also increased. Health care providers treating malignancies should be aware of this side effect and know how to diagnose and treat it.
Competing Interests: Conflict of interestThe authors have no conflicts of interest.
(© The Author(s) under exclusive licence to The Japan Society of Clinical Oncology 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
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