Reversal of Basal Ganglia Hypermetabolism Following Surgical Removal of Adrenocorticotropic Hormone-Producing Lung Carcinoid in a Patient of Cushing Syndrome With Unusual Presentation of Acute Psychosis: Proof of Concept.

Autor:	Malhotra G, Kasaliwal R; Department of Endocrinology, Mahatma Gandhi Hospital and Medical College, Jaipur, India., Rupani K; Department of Psychiatry, Seth G.S. Medical College and KEM Hospital, Mumbai, India., Lila AR; Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, India., Upadhye T; From the Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, India., Bandgar T; Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, India., Shah NS; Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, India.
Jazyk:	angličtina
Zdroj:	Clinical nuclear medicine [Clin Nucl Med] 2024 Dec 01; Vol. 49 (12), pp. e705-e707. Date of Electronic Publication: 2024 Oct 14.
DOI:	10.1097/RLU.0000000000005531
Abstrakt:	Abstract: A 34-year-old woman who presented with severe psychosis and clinical features of Cushing syndrome underwent 18 F-FDG PET/CT that revealed hypermetabolic lung lesion along with predominantly increased metabolism of bilateral basal ganglia, a scintigraphic correlate of acute psychosis. The lesion was surgically excised and histopathologically proven to be adrenocorticotropic hormone-producing lung carcinoid. Posttreatment 18 F-FDG PET scan showed restoration of normal brain metabolism with complete reversal of psychosis. Even though rare, one should be aware of psychosis as an initial presentation of Cushing syndrome and use of 18 F-FDG PET/CT for mapping brain metabolism as shown in this case. Competing Interests: Conflicts of interest and sources of funding: none declared. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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