Roadmap on magnetic nanoparticles in nanomedicine.

Autor:	Wu K; Department of Electrical and Computer Engineering, Texas Tech University, Lubbock, TX, United States of America., Wang JP; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States of America., Natekar NA; Western Digital Corporation, San Jose, CA, United States of America., Ciannella S; Department of Chemical Engineering, Texas Tech University, Lubbock, TX, United States of America., González-Fernández C; Department of Chemical Engineering, Texas Tech University, Lubbock, TX, United States of America.; Department of Chemical and Biomolecular Engineering, University of Cantabria, Santander, Spain., Gomez-Pastora J; Department of Chemical Engineering, Texas Tech University, Lubbock, TX, United States of America., Bao Y; Department of Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, AL, United States of America., Liu J; Western Digital Corporation, San Jose, CA, United States of America., Liang S; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, United States of America., Wu X; William G Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, United States of America., Nguyen T Tran L; Department of Chemical Engineering, Texas Tech University, Lubbock, TX, United States of America., Mercedes Paz González K; Department of Chemical Engineering, Texas Tech University, Lubbock, TX, United States of America., Choe H; William G Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, United States of America., Strayer J; William G Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, United States of America., Iyer PR; William G Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, United States of America., Chalmers J; William G Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, United States of America., Chugh VK; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States of America., Rezaei B; Department of Electrical and Computer Engineering, Texas Tech University, Lubbock, TX, United States of America., Mostufa S; Department of Electrical and Computer Engineering, Texas Tech University, Lubbock, TX, United States of America., Tay ZW; National Institute of Advanced Industrial Science and Technology (AIST), Health and Medical Research Institute, Tsukuba, Ibaraki 305-8564, Japan., Saayujya C; Department of Electrical Engineering and Computer Sciences, University of California Berkeley, Berkeley, CA, United States of America., Huynh Q; Department of Electrical Engineering and Computer Sciences, University of California Berkeley, Berkeley, CA, United States of America., Bryan J; Department of Bioengineering, University of California Berkeley, Berkeley, CA, United States of America., Kuo R; Department of Bioengineering, University of California Berkeley, Berkeley, CA, United States of America., Yu E; Department of Bioengineering, University of California Berkeley, Berkeley, CA, United States of America., Chandrasekharan P; Department of Bioengineering, University of California Berkeley, Berkeley, CA, United States of America., Fellows B; Magnetic Insight, Alameda, CA, United States of America., Conolly S; Department of Electrical Engineering and Computer Sciences, University of California Berkeley, Berkeley, CA, United States of America.; Department of Bioengineering, University of California Berkeley, Berkeley, CA, United States of America., Hadimani RL; Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA, United States of America.; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, United States of America.; Department of Psychiatry, Harvard Medical School, Harvard University, Boston, MA, United States of America., El-Gendy AA; Department of Physics, University of Texas at El Paso, El Paso, TX, United States of America., Saha R; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States of America., Broomhall TJ; Healthcare Technologies Institute, School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, United Kingdom., Wright AL; Healthcare Technologies Institute, School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, United Kingdom., Rotherham M; Healthcare Technologies Institute, School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, United Kingdom.; National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, Institute of Translational Medicine, Birmingham, United Kingdom., El Haj AJ; Healthcare Technologies Institute, School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, United Kingdom.; National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, Institute of Translational Medicine, Birmingham, United Kingdom., Wang Z; Spin-X Institute, School of Chemistry and Chemical Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, Guangdong Province, People's Republic of China., Liang J; Spin-X Institute, School of Chemistry and Chemical Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, Guangdong Province, People's Republic of China., Abad-Díaz-de-Cerio A; Dpto. Inmunología, Microbiología y Parasitología, Universidad del País Vasco-UPV/EHU, Leioa, Spain., Gandarias L; Bioscience and Biotechnology Institute of Aix-Marseille (BIAM), Aix-Marseille Université, CNRS, CEA-UMR 7265, Saint-Paul-lez-Durance, France.; Dpto. Electricidad y Electrónica, Universidad del País Vasco-UPV/EHU, Leioa, Spain., Gubieda AG; Dpto. Inmunología, Microbiología y Parasitología, Universidad del País Vasco-UPV/EHU, Leioa, Spain., García-Prieto A; Dpto. Física Aplicada, Universidad del País Vasco-UPV/EHU, Bilbao, Spain., Fdez-Gubieda ML; Dpto. Electricidad y Electrónica, Universidad del País Vasco-UPV/EHU, Leioa, Spain.
Jazyk:	angličtina
Zdroj:	Nanotechnology [Nanotechnology] 2024 Nov 05; Vol. 36 (4). Date of Electronic Publication: 2024 Nov 05.
DOI:	10.1088/1361-6528/ad8626
Abstrakt:	Magnetic nanoparticles (MNPs) represent a class of small particles typically with diameters ranging from 1 to 100 nanometers. These nanoparticles are composed of magnetic materials such as iron, cobalt, nickel, or their alloys. The nanoscale size of MNPs gives them unique physicochemical (physical and chemical) properties not found in their bulk counterparts. Their versatile nature and unique magnetic behavior make them valuable in a wide range of scientific, medical, and technological fields. Over the past decade, there has been a significant surge in MNP-based applications spanning biomedical uses, environmental remediation, data storage, energy storage, and catalysis. Given their magnetic nature and small size, MNPs can be manipulated and guided using external magnetic fields. This characteristic is harnessed in biomedical applications, where these nanoparticles can be directed to specific targets in the body for imaging, drug delivery, or hyperthermia treatment. Herein, this roadmap offers an overview of the current status, challenges, and advancements in various facets of MNPs. It covers magnetic properties, synthesis, functionalization, characterization, and biomedical applications such as sample enrichment, bioassays, imaging, hyperthermia, neuromodulation, tissue engineering, and drug/gene delivery. However, as MNPs are increasingly explored for in vivo applications, concerns have emerged regarding their cytotoxicity, cellular uptake, and degradation, prompting attention from both researchers and clinicians. This roadmap aims to provide a comprehensive perspective on the evolving landscape of MNP research. (Creative Commons Attribution license.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu