Peri-implant medication-related osteonecrosis of the jaw mimicking endodontic disease in a cancer patient: A case report.

Autor: Rocha AC; Department of Oral Medicine, A.C. Camargo Cancer Center, São Paulo, Brazil.; Department of Dentistry, Clinics Hospital, University of São Paulo, São Paulo, Brazil., Mota ME; Department of Stomatology, School of Dentistry, University of São Paulo (USP), São Paulo, Brazil., Lima RC; Department of Hospital Dentistry, Hospital Paulistano, São Paulo, Brazil., Pereira NF; Department of Hospital Dentistry, Hospital Paulistano, São Paulo, Brazil., Alves FA; Department of Oral Medicine, A.C. Camargo Cancer Center, São Paulo, Brazil.; Department of Stomatology, School of Dentistry, University of São Paulo (USP), São Paulo, Brazil., Moreira MS; Department of Oral Medicine, A.C. Camargo Cancer Center, São Paulo, Brazil.; Department of Stomatology, School of Dentistry, University of São Paulo (USP), São Paulo, Brazil.
Jazyk: angličtina
Zdroj: Australian endodontic journal : the journal of the Australian Society of Endodontology Inc [Aust Endod J] 2024 Oct 12. Date of Electronic Publication: 2024 Oct 12.
DOI: 10.1111/aej.12893
Abstrakt: Medication-related osteonecrosis of the jaw (MRONJ) is a progressive condition that can cause significant bone loss and its diagnosis can be challenging. A 68-year-old man with a diagnosis of hepatocellular carcinoma, undergoing treatment with atezolizumab, bevacizumab and zoledronic acid, complained of spontaneous pain in the right lower second premolar. Oral examination revealed no dental changes and implants in the right jaw. A patient history and thorough clinical and radiographic examinations mimic endodontic disease. The implant crowns were removed, bleeding on probing, and peri-implant pockets were observed. The main hypothesis was MRONJ Stage 2, and the surgical treatment was performed. The pain ceased and signs of MRONJ were not observed within 3 months. MRONJ should be considered as a hypothesis in the case of odontalgia and a patient's history of antiresorptive and antiangiogenic therapies. Furthermore, monitoring patients with dental implants in the mandible through detailed clinical and imaging evaluation is required.
(© 2024 Australian Society of Endodontology Inc.)
Databáze: MEDLINE
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