Oxygenation associated with cord management strategies among preterm infants <32 weeks gestation during the transition period.

Autor: Peterson C; Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, USA.; Department of Pharmaceutical & Clinical Sciences, Campbell University, Buies Creek, NC, USA., Ferrer L; Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, USA.; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Sanjay S; Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, USA., Poeltler D; Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, USA., Lakshminrusimha S; Department of Pediatrics, University of California at Davis, Sacramento, CA, USA., Katheria AC; Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, USA. anup.katheria@sharp.com.
Jazyk: angličtina
Zdroj: Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2024 Oct 11. Date of Electronic Publication: 2024 Oct 11.
DOI: 10.1038/s41372-024-02127-7
Abstrakt: Objective: Compare changes in SpO 2 and FiO 2 post-birth among preterm infants after delayed cord clamping (DCC), umbilical cord milking (UCM) or early cord clamping (ECC).
Study Design: Retrospective study of infants <32 weeks gestation born between 2014 and 2021. ECC was clamping 0-59 s, DCC was clamping ≥60 s after delivery, UCM defined as milking the intact umbilical cord several times before clamping.
Results: Of 463 infants; 257 received DCC, 168 received UCM, 38 received ECC. UCM infants had higher median SpO 2 values at 4-(79% UCM vs 69% DCC, p = 0.027) and 5-(85% UCM vs 80% DCC, p = 0.023) minutes after-birth compared to DCC. DCC and UCM infants required lower FiO 2 levels in the first 5-minutes compared to ECC infants (DCC 0.38 ± 0.17, UCM 0.40 ± 0.20 vs ECC 0.51 ± 0.27, p's <0.001).
Conclusion: The proportion of infants achieving SpO 2  ≥ 80% by 5 min was similar in all groups, FiO 2 needed to achieve this goal was higher in ECC infants.
(© 2024. The Author(s), under exclusive licence to Springer Nature America, Inc.)
Databáze: MEDLINE
Externí odkaz: