Green synthesis of thiazole bis-imines as fluorometric sensor for determination of lead in environmental, biological, and food samples.

Autor: da Silva Oliveira CR; Departamento de Química, Centro de Ciências Exatas e Tecnológicas, Federal University of Viçosa, Viçosa, MG 36570-900, Brazil., Suarez WT; Departamento de Química, Centro de Ciências Exatas e Tecnológicas, Federal University of Viçosa, Viçosa, MG 36570-900, Brazil. Electronic address: williants@ufv.br., Dos Santos Melo G; Departamento de Química, Centro de Ciências Exatas e Tecnológicas, Federal University of Viçosa, Viçosa, MG 36570-900, Brazil., Barros AO; Grupo de Química Supramolecular e Biomimética (GQSB), Departamento de Química, CCE, Federal University of Viçosa, Viçosa, MG 36570-900, Brazil., Dias Castro GA; Grupo de Química Supramolecular e Biomimética (GQSB), Departamento de Química, CCE, Federal University of Viçosa, Viçosa, MG 36570-900, Brazil., Fernandes SA; Grupo de Química Supramolecular e Biomimética (GQSB), Departamento de Química, CCE, Federal University of Viçosa, Viçosa, MG 36570-900, Brazil., de Almeida JPB; Laboratório de Instrumentação e Automação em Analítica Aplicada (LIA), Federal University of Pernambuco, Recife, PE, Brazil., Dos Santos VB; Laboratório de Instrumentação e Automação em Analítica Aplicada (LIA), Federal University of Pernambuco, Recife, PE, Brazil.
Jazyk: angličtina
Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2025 Feb 05; Vol. 326, pp. 125250. Date of Electronic Publication: 2024 Oct 05.
DOI: 10.1016/j.saa.2024.125250
Abstrakt: In this work, we describe for the first time the synthesis of a thiazole bis-imine fluorometric sensor for the selective determination of Pb 2+ in environmental, biological, and food samples. The novel molecules were obtained through a multicomponent reaction using a green and environmentally sustainable methodology. Synthesized chemical sensors were characterized using spectroscopic techniques to structural elucidation, including UV-Vis, FTIR-ATR, 1 H and 13 C NMR. One of these sensors exhibited remarkable selectivity for the Pb 2+ ion at pH 3, forming a stable 1:1 (metal:ligand) complex. Additionally, the reaction conditions for complex formation were optimized, resulting in a method with a linear range of 0.667-10  μg L -1 and a detection limit of 0.18  μg L -1 . Furthermore, method validation reinforced its reliability, showing low relative standard deviation in both intra-day and inter-day analyses. Recovery experiments ranged from 83.53 % to 119.10 %. This study represents a significant and innovative advancement in the development of rapid, sensitive, and alternative methods for the detection of potentially toxic metals in a wide range of samples employing a green multicomponent reaction of thiazole bis-imines.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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