Investigation of the Effectiveness of Nasal Sprays in Allergic Rhinitis.

Autor:	Güner Atayoğlu A; Department of Family Medicine, Atatürk Family Health Center, İstanbul, Turkey., Bayar Muluk N; Department of Otorhinolaryngology, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey., Koca R; ENT Clinic, Antalya Training and Research Hospital, Antalya, Turkey., Çukurova İ; Department of Otorhinolaryngology, Izmir Faculty of Medicine, Tepecik Training and Research Hospital, University of Health Sciences, Izmir, Turkey., Çetinkaya EA; ENT Clinic, Antalya Training and Research Hospital, Antalya, Turkey., Yörük Ö; Department of Otorhinolaryngology, Faculty of Medicine, Atatürk University, Erzurum, Turkey., Bal C; Department of Biostatistics, Faculty of Medicine, Eskişehir Osmangazi University, Eskişehir, Turkey., Tatar A; Department of Otorhinolaryngology, Faculty of Medicine, Atatürk University, Erzurum, Turkey., Susaman N; ENT Clinic, Elazığ Fethi Sekin City Hospital, University of Health Sciences, Elazığ, Turkey., Erdoğmuş Küçükcan ND; ENT Clinic, Adana City Training and Research Hospital, Adana, Turkey., Güngör E; Department of Otorhinolaryngology, Faculty of Medicine, Eskişehir Osmangazi University, Eskişehir, Turkey., Özçelik N; ENT Clinic, Esenler Health Application Center, Medipol University, İstanbul, Turkey., Alaskarov E; ENT Clinic, Esenler Health Application Center, Medipol University, İstanbul, Turkey., Öztürk Z; Department of Otorhinolaryngology, Faculty of Medicine, Istanbul Nişantaşı University, Istanbul, Turkey.; Otolaryngology Clinics, Baypark Hospital, Istanbul, Turkey., Oğuz O; Dr. Oğuzhan Oğuz Wellnose Clinic, Istanbul, Turkey., Taş BM; Department of Otorhinolaryngology, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey., Cingi C; Department of Otorhinolaryngology, Faculty of Medicine, Eskişehir Osmangazi University, Eskişehir, Turkey.
Jazyk:	angličtina
Zdroj:	Ear, nose, & throat journal [Ear Nose Throat J] 2024 Nov; Vol. 103 (3_suppl), pp. 144S-151S. Date of Electronic Publication: 2024 Oct 10.
DOI:	10.1177/01455613241287298
Abstrakt:	Objectives: We investigated the effectiveness of different types of nasal irrigation sprays in adult allergic rhinitis (AR) patients. Methods: A total of 1700 patients with AR (866 males and 834 females) were assigned to: Group 1: Hypertonic nasal spray group ( n = 600) (Sinomarin ® hypertonic nasal spray); Group 2: Algae-containing hypertonic nasal spray group ( n = 600) (Sinomarin Plus Algae ENT); and Group 3: Isotonic saline nasal spray group ( n = 500). All patients underwent an otolaryngological examination, continued their standard AR treatment, and received the assigned nasal spray additionally (1 spray to each nostril, 3 times a day, for 3 weeks). Allergic symptom scores, turbinate examination, total symptom scores, and quality of life (QoL) scores were evaluated during pre- and post-treatment periods. Results: In groups 1 and 2, symptom scores and turbinate color and edema, total symptom scores, and QoL scores increased after treatment ( P < .05). In the saline group, there were no significant differences in symptom scores and total symptom scores after treatment; however, improvement was detected in turbinate color and edema values after treatment. QoL scores increased after treatment. When comparing the 3 groups, the total symptom scores of groups 1 and 2 were significantly lower, and the QoL scores of groups 1 and 2 were considerably higher than those of the saline group. There were no significant differences between groups 1 and 2. Conclusion: Algae-containing and hypertonic nasal spray may be added to the standard AR treatment to increase QoL and decrease total symptom scores. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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